Evidence map›Paper›PMID 34299680›Full record

ArticleInternational journal of environmental research and public health2021

Alterations in Circulating MicroRNAs and the Relation of MicroRNAs to Maximal Oxygen Consumption and Intima-Media Thickness in Ultra-Marathon Runners.

Ceren Eyileten, Alex Fitas, Daniel Jakubik, Pamela Czajka, Anna Mróz, Anna Czajkowska, Katarzyna Witek, Wawrzyniec Bakalarski, Salvatore De Rosa, Marek Postuła and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Non-coding RNAs in exercise immunology: A systematic review.Journal of sport and health science · 2024
    Pooled it
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ceren EyiletenCenter for Preclinical Research and Technology CEPT, Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Alex FitasCenter for Preclinical Research and Technology CEPT, Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Daniel JakubikCenter for Preclinical Research and Technology CEPT, Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Pamela CzajkaCenter for Preclinical Research and Technology CEPT, Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-0193-0192
Anna MrózDepartment of Physical Education, Józef Piłsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.ORCID 0000-0001-7169-5493
Anna CzajkowskaDepartment of Tourism and Recreation, Józef Piłsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.ORCID 0000-0002-2128-0131
Katarzyna WitekDepartment of Tourism and Recreation, Józef Piłsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.
Wawrzyniec BakalarskiDepartment of Tourism and Recreation, Józef Piłsudski University of Physical Education in Warsaw, 00-809 Warsaw, Poland.
Salvatore De RosaDivision of Cardiology, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0001-5388-942X
Marek PostułaCenter for Preclinical Research and Technology CEPT, Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0002-7826-4458
Łukasz A MałekDepartment of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology, 04-628 Warsaw, Poland.ORCID 0000-0002-9586-0163
Medical University of Warsaw · PLJózef Piłsudski University of Physical Education in Warsaw · PLInstitute of Cardiology · PLMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of long-term training on cardiovascular disease (CVD) is not clear. Carotid intima-media thickness (CIMT) test is recommended as a useful measure to diagnose the early stages of atherosclerosis. MicroRNAs (miRNAs) are altered due to endurance exercise and can be promising biomarkers of pathophysiological changes. We aimed to evaluate the association of circulating miRNAs with physical fitness and markers of atherosclerosis in ultra-marathon runners. Ultra-marathon runners had 28-fold upregulation of miR-125a-5p expressions compared to control individuals (

Indexed as

Circulating MicroRNAMicroRNAsCarotid Intima-Media ThicknessHumansMarathon RunningOxygen ConsumptionCirculating MicroRNAMicroRNAsatherosclerosiscardiovascular diseaseendurance sportmicroRNAmiRNA

Identifiers

PMID34299680
PMCPMC8307599
OpenAlexW3182590825

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.