Evidence map›Paper›PMID 34299687›Full record

SynthesisInternational journal of environmental research and public health2021

Can Physical Activity Reduce the Risk of Cognitive Decline in Apolipoprotein e4 Carriers? A Systematic Review.

Jose Luis Perez-Lasierra, Jose Antonio Casajús, José Antonio Casasnovas, Jose Miguel Arbones-Mainar, Antonio Lobo, Elena Lobo, Belén Moreno-Franco, Alejandro Gonzalez-Agüero

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jose Luis Perez-LasierraDepartment of Physiatry and Nursing, Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-1113-9169
Jose Antonio CasajúsDepartment of Physiatry and Nursing, Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-7215-6931
José Antonio CasasnovasInstituto de Investigación Sanitaria Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.ORCID 0000-0002-9887-2629
Jose Miguel Arbones-MainarCIBEROBN Instituto de Salud Carlos III, 28029 Madrid, Spain.
Antonio LoboInstituto de Investigación Sanitaria Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.ORCID 0000-0002-9098-655X
Elena LoboInstituto de Investigación Sanitaria Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.ORCID 0000-0002-1252-2397
Belén Moreno-FrancoInstituto de Investigación Sanitaria Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.ORCID 0000-0003-0604-5042
Alejandro Gonzalez-AgüeroDepartment of Physiatry and Nursing, Universidad de Zaragoza, 50009 Zaragoza, Spain.ORCID 0000-0002-1132-5906
Universidad de Zaragoza · ESInstituto de Salud Carlos III · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) reduces the risk of cognitive decline (CD) in the general population. However, little is known about whether the presence of the apolipoprotein E epsilon 4 allele (

Indexed as

Apolipoprotein E4Cognitive DysfunctionAllelesApolipoproteins EExerciseGenotypeHumansLongitudinal StudiesApolipoprotein E4Apolipoproteins EAPOE e4Cognitive Dysfunctionexercisemild cognitive impairment

Identifiers

PMID34299687
PMCPMC8303365
OpenAlexW3181228793

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.