Evidence map›Paper›PMID 34311241›Full record

ArticleFood chemistry2022

Computational modeling predicts potential effects of the herbal infusion "horchata" against COVID-19.

Eduardo Tejera, Yunierkis Pérez-Castillo, Gisselle Toscano, Ana Lucía Noboa, Valeria Ochoa-Herrera, Francesca Giampieri, José M Álvarez-Suarez

Open access · greenAbstract read
In one paragraph

Article in Food chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Molecules (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Inhibition of the main protease of SARS-CoV-2 (MComputational and structural biotechnology journal · 2022
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Eduardo TejeraGrupo de Bio-Quimioinformática, Universidad de Las Américas, Quito, Ecuador; Facultad de Ingeniería y Ciencias Aplicadas, Universidad de Las Américas, Quito, Ecuador. Electronic address: eduardo.tejera@udla.edu.ec.
Yunierkis Pérez-CastilloGrupo de Bio-Quimioinformática, Universidad de Las Américas, Quito, Ecuador; Escuela de Ciencias Físicas y Matemáticas, Universidad de Las Américas, Quito, Ecuador.
Gisselle ToscanoFacultad de Ingeniería y Ciencias Aplicadas, Universidad de Las Américas, Quito, Ecuador.
Ana Lucía NoboaColegio de Ciencias e Ingenierías, Instituto Biósfera, Universidad San Francisco de Quito, Quito, Ecuador.
Valeria Ochoa-HerreraColegio de Ciencias e Ingenierías, Instituto Biósfera, Universidad San Francisco de Quito, Quito, Ecuador; Department of Environmental Sciences and Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, United States.
Francesca GiampieriDepartment of Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
José M Álvarez-SuarezDepartamento de Ingeniería en Alimentos, Colegio de Ciencias e Ingenierías, Universidad San Francisco de Quito, Quito, Ecuador; Instituto de Investigaciones en Biomedicina iBioMed, Universidad San Francisco de Quito, Quito, Ecuador; King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: jalvarez@usfq.edu.ec.
Universidad de Las Américas · ECUniversidad San Francisco de Quito · ECKing Abdulaziz University · SAMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive plant-derived molecules have emerged as therapeutic alternatives in the fight against the COVID-19 pandemic. In this investigation, principal bioactive compounds of the herbal infusion "horchata" from Ecuador were studied as potential novel inhibitors of the SARS-CoV-2 virus. The chemical composition of horchata was determined through a HPLC-DAD/ESI-MS

Indexed as

COVID-19HumansMolecular Docking SimulationMolecular Dynamics SimulationPandemicsProtease InhibitorsSARS-CoV-2Protease InhibitorsCOVID-19DockingGene ontologyHerbal infusionHorchata infusionMolecular dynamicsSARS-CoV-2

Identifiers

PMID34311241
PMCPMC8314115
OpenAlexW3177635061

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.