Evidence map›Paper›PMID 34313972›Full record

ArticleJournal of endocrinological investigation2022

Metabolic syndrome is not associated to an increased risk of low bone mineral density in men at risk for osteoporosis.

D Rendina, L D'Elia, G De Filippo, V Abate, M Evangelista, A Giaquinto, B Barone, G Piccinocchi, D Prezioso, P Strazzullo

Abstract read
In one paragraph

Article in Journal of endocrinological investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The Role of Testosterone in the Elderly: What Do We Know?International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

D RendinaDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.
L D'EliaDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.
G De FilippoAssistance Publique-Hôpitaux de Paris, Hôpital Robert-Debré, Service d'Endocrinologie et Diabétologie, 48, Boulevard Sérurier, 75019, Paris, France. gianpaolo.defilippo@aphp.fr.ORCID http://orcid.org/0000-0003-1313-5599
V AbateDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.
M EvangelistaDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.
A GiaquintoDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.
B BaroneDepartment of Neuroscience Reproductive Sciences and Dentistry, Federico II University, 80131, Naples, Italy.
G Piccinocchi"COMEGEN" Medical Cooperative, 80126, Naples, Italy.
D PreziosoDepartment of Neuroscience Reproductive Sciences and Dentistry, Federico II University, 80131, Naples, Italy.
P StrazzulloDepartment of Clinical Medicine and Surgery, Federico II University, 80131, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe have recently demonstrated a significant association between osteoporosis (Op) and metabolic syndrome (MetS) in Caucasian women examined by Dual-energy X-ray absorptiometry (DXA) for suspected Op. This cross-sectional study was performed to evaluate the association between MetS and Op in Caucasian men enrolled in the same geographical area, with identical criteria and in the same time range.

methodsAmong subjects enrolled in the SIMON study, we selected the medical records of all free-living men who performed a contextual evaluation of both bone mineral density (BMD) by DXA and MetS constitutive elements (arterial blood pressure, waist circumference, serum levels of triglycerides, high-density lipoprotein cholesterol, and fasting glucose). All enrolled subjects refer to "COMEGEN" general practitioners' cooperative operating in Naples, Southern Italy.

resultsOverall, the medical records of 880 men were examined. No significant association between MetS and Op was observed. Among MetS constitutive elements, waist circumference was inversely related to Op risk.

conclusionIn Caucasian men examined by DXA for suspected Op, no significant association was observed between Op and MetS. The study results contrast to those observed in women enrolled in the same geographical area, with identical criteria and in the same time range and may be related to sexual dimorphism occurring in clinical expressiveness of both MetS and Op.

Indexed as

Absorptiometry, PhotonMetabolic SyndromeOsteoporosisAgedBlood GlucoseBone DensityCross-Sectional StudiesHumansIndependent LivingItalyLumbar VertebraeMaleMedical RecordsNegative ResultsRisk FactorsWaist CircumferenceBlood GlucoseEpidemiological surveyMetabolic syndromeOsteoporosisWaist circumference

Identifiers

PMID34313972
PMCPMC8783849

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.