Evidence map›Paper›PMID 34318684›Full record

ArticleEpigenomics2021

Cataloging recent advances in epigenetic alterations in major mental disorders and autism.

Hamid Mostafavi Abdolmaleky, Jin-Rong Zhou, Sam Thiagalingam

Open access · greenAbstract read
In one paragraph

Article in Epigenomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. EpiBrain: the brain's epigenetic landscape in a snapshot.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Methylation ofFrontiers in genetics · 2024
    Article
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hamid Mostafavi AbdolmalekyDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, 02118 MA, USA.ORCID 0000-0002-8872-5174
Jin-Rong ZhouDepartment of Surgery, Nutrition/Metabolism Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, 02215 MA, USA.ORCID 0000-0002-6745-9495
Sam ThiagalingamDepartment of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, 02118 MA, USA.ORCID 0000-0001-5211-266X
Boston University · USBeth Israel Deaconess Medical Center · US

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Illuminating Dynamic Receptor Clustering in the Epidermal Growth Factor Receptor Signal Transduction Pathway Using Plasmon CouplingR01CA138509 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Bjoern Markus Reinhard · 2009 to 2026
$5.9M
Multiplexed Imaging in the Near Infrared with Indium Phosphide Quantum ShellsR01GM129437 · NIGMS · NORTHEASTERN UNIVERSITY · PI DENNIS, ALLISON MARIE · 2019 to 2022
$2.1M
Dissecting the metastasis suppressor complex to identify colon cancer biomarkersR21CA165707 · NCI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI THIAGALINGAM, SAM · 2013 to 2014
$386k
NCATS NIH HHS UL1 TR001430NCI NIH HHS R01 CA138509NCI NIH HHS R21 CA165707NIGMS NIH HHS R01 GM129437
6 · The paper itself

Abstract

During the last two decades, diverse epigenetic modifications including DNA methylation, histone modifications, RNA editing and miRNA dysregulation have been associated with psychiatric disorders. A few years ago, in a review we outlined the most common epigenetic alterations in major psychiatric disorders (e.g., aberrant DNA methylation of

Indexed as

Disease SusceptibilityEpigenesis, GeneticGenetic VariationAutistic DisorderBiomarkersDNA MethylationGene Expression Regulation, NeoplasticGenetic Predisposition to DiseaseHumansMental DisordersMicroRNAsPhenotypeRisk FactorsBiomarkersMicroRNAsDTNBP1HTR2AHTR4LINE-1MB-COMTmiR-137miR-181bmiR-34amiR-451aRELN

Identifiers

PMID34318684
PMCPMC8738978
OpenAlexW3183170800

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.