Evidence mapPaperPMID 34325840Full record

ReviewJournal of the American College of Cardiology2021

Management of Obesity in Cardiovascular Practice: JACC Focus Seminar.

Jean-Pierre Després, André C Carpentier, André Tchernof, Ian J Neeland, Paul Poirier

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05987410 (EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Diabetic patiEnts With Cardiovascular Disease. The VENERE Study), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05987410 narecruitingnot on this mapstarted 2023, after this paper: background citation

EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Diabetic patiEnts With Cardiovascular Disease. The VENERE Study

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2023 to 2026Enrolled105ConditionsCardiovascular Diseases, Diabete Type 2, Overweight and ObesityArmsNordic Walking (NW), Standard Rehabilitation (SR), Cardiological Counselling (CC)
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
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  16. Definition and diagnostic criteria of clinical obesity.The lancet. Diabetes & endocrinology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jean-Pierre DesprésVITAM-Centre de recherche en santé durable, CIUSSS de la Capitale-Nationale, Québec, Québec, Canada; Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Québec, Québec, Canada; Department of Kinesiology, Faculty of Medicine, Université Laval, Québec, Québec, Canada. Electronic address: Jean-Pierre.Despres.ciussscn@ssss.gouv.qc.ca.
André C CarpentierCentre de recherche du Centre hospitalier universitaire de Sherbrooke, Sherbrooke, Québec, Canada; Department of Medicine, Division of Endocrinology, Université de Sherbrooke, Sherbrooke, Québec, Canada. Electronic address: https://twitter.com/CarpentierAndr3.
André TchernofCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Québec, Québec, Canada; School of Nutrition, Université Laval, Québec, Québec, Canada.
Ian J NeelandUniversity Hospitals Harrington Heart and Vascular Institute and Case Western Reserve University, Cleveland, Ohio, USA.
Paul PoirierCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval, Québec, Québec, Canada; Faculty of Pharmacy, Université Laval, Québec, Québec, Canada.
Institut universitaire de cardiologie et de pneumologie de Québec · CAInstitut Universitaire en Santé Mentale de Québec · CAUniversité de Sherbrooke · CAUniversity Hospitals of Cleveland · US

Funding

CIHR FDN-167278NIDDK NIH HHS K23 DK106520
6 · The paper itself

Abstract

Obesity contributes to reduced life expectancy because of its link with type 2 diabetes and cardiovascular disease. Yet, targeting this poorly diagnosed, ill-defined, and underaddressed modifiable risk factor remains a challenge. In this review, we emphasize that the tendency among health care professionals to amalgam all forms of obesity altogether as a single entity may contribute to such difficulties and discrepancies. Obesity is a heterogeneous condition both in terms of causes and health consequences. Attention should be given to 2 prevalent subgroups of individuals: 1) patients who are overweight or moderately obese with excess visceral adipose tissue; and 2) patients with severe obesity, the latter group having distinct additional health issues related to their large body fat mass. The challenge of tackling high-cardiovascular-risk forms of obesity through a combination of personalized clinical approaches and population-based solutions is compounded by the current obesogenic environment and economy.

Indexed as

CardiologyCardiovascular DiseasesHumansObesitycardiovascular diseaseectopic fat depositionmassive obesitytype 2 diabetesvisceral obesity

Identifiers

PMID34325840
PMCPMC8609918
OpenAlexW3186621629

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.