Evidence map›Paper›PMID 34326390›Full record

ArticleScientific reports2021

Ontology of the apelinergic system in mouse pancreas during pregnancy and relationship with β-cell mass.

Brenda Strutt, Sandra Szlapinski, Thineesha Gnaneswaran, Sarah Donegan, Jessica Hill, Jamie Bennett, David J Hill

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Brenda StruttLawson Health Research Institute, St Joseph Health Care, 268 Grosvenor St, London, ON, N6A 4V2, Canada.
Sandra SzlapinskiLawson Health Research Institute, St Joseph Health Care, 268 Grosvenor St, London, ON, N6A 4V2, Canada.
Thineesha GnaneswaranDepartment of Physiology and Pharmacology, Western University, London, ON, N6A 3K7, Canada.
Sarah DoneganDepartment of Physiology and Pharmacology, Western University, London, ON, N6A 3K7, Canada.
Jessica HillInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, EX2 5DW, UK.
Jamie BennettLawson Health Research Institute, St Joseph Health Care, 268 Grosvenor St, London, ON, N6A 4V2, Canada.
David J HillLawson Health Research Institute, St Joseph Health Care, 268 Grosvenor St, London, ON, N6A 4V2, Canada. david.hill@lawsonresearch.com.ORCID http://orcid.org/0000-0002-2490-5678
Western University · CALawson Health Research Institute · CAUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The apelin receptor (Aplnr) and its ligands, Apelin and Apela, contribute to metabolic control. The insulin resistance associated with pregnancy is accommodated by an expansion of pancreatic β-cell mass (BCM) and increased insulin secretion, involving the proliferation of insulin-expressing, glucose transporter 2-low (Ins

Indexed as

Pregnancy, AnimalAnimalsApelinApelin ReceptorsCell ProliferationCell SeparationFemaleFlow CytometryGene Expression ProfilingGlucose IntoleranceInsulinInsulin ResistanceInsulin-Secreting CellsIntercellular Signaling Peptides and ProteinsInterleukin-6MiceApelinapelin-13 peptideApelin ReceptorsInsulinIntercellular Signaling Peptides and ProteinsInterleukin-6interleukin-6, mouse

Identifiers

PMID34326390
PMCPMC8322410
OpenAlexW3184407694

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.