Evidence map›Paper›PMID 34326695›Full record

ArticleInternational journal of biological sciences2021

Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice.

Youxi Yu, Xiaoju Shi, Qianqian Zheng, Xingtong Wang, Xingkai Liu, Min Tan, Guoyue Lv, Ping Zhang, Robert C Martin, Yan Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
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  8. Genomic Relevance ofJournal of clinical medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Youxi YuDepartment of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
Xiaoju ShiDepartment of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
Qianqian ZhengDepartment of Pathophysiology, Basic Medicine College, China Medical University, Shenyang 110122, China.
Xingtong WangDepartment of Tumor Center, The First Hospital of Jilin University, Changchun, Jilin, China.
Xingkai LiuDepartment of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130021, China.
Min TanDepartment of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
Guoyue LvDepartment of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130021, China.
Ping ZhangDepartment of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun 130021, China.
Robert C MartinDepartment of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
Yan LiDepartment of Surgery, School of Medicine, University of Louisville, Louisville, KY 40202, USA.
Jilin University · CNUniversity of Louisville · USFirst Hospital of Jilin University · CNChina Medical University · CN

Funding

Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI HOOD, JOSHUA L. · 2016 to 2025
$24.1M
NIGMS NIH HHS P20 GM113226
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Signal TransductionAcrylamidesAnimalsCaco-2 CellsCarcinoma, HepatocellularDiet, High-FatFibroblast Growth FactorsHepatocytesHumansLiver NeoplasmsMaleMiceMice, Inbred C57BLMice, KnockoutNon-alcoholic Fatty Liver DiseaseQuinazolinesAcrylamidesBLU9931Fgfr4 protein, mousefibroblast growth factor 21Fibroblast Growth FactorsQuinazolinesReceptor, Fibroblast Growth Factor, Type 4Bile acid.Fibroblast growth factor 15/19Fibroblast growth factor 21Nonalcoholic fatty liver diseaseNonalcoholic steatohepatities

Identifiers

PMID34326695
PMCPMC8315028
OpenAlexW3184167413

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.