Evidence mapPaperPMID 34328155Full record

ArticleMolecular omics2021

Transcriptome features of striated muscle aging and predictability of protein level changes.

Yu Han, Lauren Z Li, Nikhitha L Kastury, Cody T Thomas, Maggie P Y Lam, Edward Lau

Open access · greenAbstract read
In one paragraph

Article in Molecular omics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cytochrome bAging cell · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Proteogenomics reveals sex-biased aging genes and coordinated splicing in cardiac aging.American journal of physiology. Heart and circulatory physiology · 2022
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yu HanDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.
Lauren Z LiDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.
Nikhitha L KasturyDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.
Cody T ThomasDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.
Maggie P Y LamDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.
Edward LauDepartment of Medicine, Consortium for Fibrosis Research & Translation, University of Colorado School of Medicine, Aurora, CO 80045, USA. edward.lau@cuanschutz.edu.ORCID 0000-0001-9083-5922
University of Colorado Denver · US

Funding

Alternative Protein Isoforms in Ventricular RemodelingR01HL141278 · UNIVERSITY OF COLORADO DENVER · 2025 to 2025
$389k
NHLBI NIH HHS F32 HL149191NHLBI NIH HHS R00 HL127302NHLBI NIH HHS R00 HL144829NHLBI NIH HHS R01 HL141278NHLBI NIH HHS R21 HL150456NIGMS NIH HHS T34 GM096958
6 · The paper itself

Abstract

We performed total RNA sequencing and multi-omics analysis comparing skeletal muscle and cardiac muscle in young adult (4 months)

Indexed as

Muscle, StriatedTranscriptomeAgingAnimalsMiceMuscle, SkeletalProteomics

Identifiers

PMID34328155
PMCPMC8511094
OpenAlexW3185619703

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.