ArticleHorticulture research2021
McMYB4 improves temperature adaptation by regulating phenylpropanoid metabolism and hormone signaling in apple.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
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- Novel cytoplasmic male sterile line development and stage-specific metabolomic profiling in rice (Oryza sativa L.) for advancing hybrid breeding technology.BMC plant biology · 2026Article
- Genome-wide identification, structural characterization, and gene expression analysis of the MYB transcription factor family in faba bean (Vicia faba L.).BMC plant biology · 2026Article
- Cold-tolerant bacteria from alpine Rosaceae plants modulate transcriptional responses of apple and strawberry plantlets to freezing stress.Frontiers in plant science · 2026Article
- Enhanced lignin and cellulose metabolism promote cell wall synthesis and growth of wild soybean HRA under alkali stress.Annals of botany · 2025Article
- PbrMYB14 Enhances Pear Resistance toInternational journal of molecular sciences · 2025Article
- Review
- Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues.Frontiers in plant science · 2025Review
- Silencing of miR169a improves drought stress by enhancing vascular architecture, ROS scavenging, and photosynthesis ofFrontiers in plant science · 2025Article
- Discovery of gene regulation mechanisms associated with uniconazole-induced cold tolerance in banana using integrated transcriptome and metabolome analysis.BMC plant biology · 2024Article
- Transcriptional regulation of flavonol biosynthesis in plants.Horticulture research · 2024Review
- Article
- Phylogenetic Analysis ofBiomolecules · 2023Article
- Effect of temperature on betacyanins synthesis and the transcriptome ofFrontiers in plant science · 2023Article
- Roles of Auxin in the Growth, Development, and Stress Tolerance of Horticultural Plants.Cells · 2022Review
- Article
- Combined Analysis of the Metabolome and Transcriptome to Explore Heat Stress Responses and Adaptation Mechanisms in Celery (International journal of molecular sciences · 2022Article
- Combined analysis of transcriptome and metabolome reveals that sugar, lipid, and phenylpropane metabolism are essential for male fertility in temperature-induced male sterile rice.Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temperature changes affect apple development and production. Phenylpropanoid metabolism and hormone signaling play a crucial role in regulating apple growth and development in response to temperature changes. Here, we found that McMYB4 is induced by treatment at 28 °C and 18 °C, and McMYB4 overexpression results in flavonol and lignin accumulation in apple leaves. Yeast one-hybrid (Y1H) assays and electrophoretic mobility shift assays (EMSAs) further revealed that McMYB4 targets the promoters of the flavonol biosynthesis genes CHS and FLS and the lignin biosynthesis genes CAD and F5H. McMYB4 expression resulted in higher levels of flavonol and lignin biosynthesis in apple during growth at 28 °C and 18 °C than during growth at 23 °C. At 28 °C and 18 °C, McMYB4 also binds to the AUX/ARF and BRI/BIN promoters to activate gene expression, resulting in acceleration of the auxin and brassinolide signaling pathways. Taken together, our results demonstrate that McMYB4 promotes flavonol biosynthesis and brassinolide signaling, which decreases ROS contents to improve plant resistance and promotes lignin biosynthesis and auxin signaling to regulate plant growth. This study suggests that McMYB4 participates in the abiotic resistance and growth of apple in response to temperature changes by regulating phenylpropanoid metabolism and hormone signaling.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.