Evidence map›Paper›PMID 34334150›Full record

ArticlePublic health nutrition2021

Association between egg intake and blood pressure in the USA: the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP).

Thanh-Huyen T Vu, Linda Van Horn, Martha L Daviglus, Queenie Chan, Alan R Dyer, Victor W Zhong, Rachel Gibson, Paul Elliott, Jeremiah Stamler

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Thanh-Huyen T VuDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-5069-4886
Linda Van HornDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois at Chicago, Chicago, IL, USA.
Queenie ChanDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Alan R DyerDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Victor W ZhongDepartment of Epidemiology and Biostatistics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Rachel Gibson5Department of Nutritional Sciences, King's College London, London, UK.
Paul ElliottDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Jeremiah StamlerDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Northwestern University · USImperial College London · GBKing's College London · GBShanghai Jiao Tong University · CNUniversity of Illinois Chicago · US

Funding

Metabolic Pathways Underlying the Contrasting Sodium-BP and DASH/OmniHeart-BP RelationshipsR01HL135486 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DAVIGLUS, MARTHA L, ELLIOTT, PAUL · 2017 to 2020
$2.6M
NHLBI NIH HHS R01 HL135486
6 · The paper itself

Abstract

objectivesTo investigate associations of egg intake with blood pressure (BP) and the role of dietary variables and other macro- and micro-nutrients in the association.

designWe used cross-sectional data for the USA as part of the INTERnational study on MAcro/micronutrients and blood Pressure (INTERMAP). INTERMAP was surveyed between 1996 and 1999, including four 24-h dietary recalls, two 24-h urine collections and eight measurements of systolic BP and diastolic BP (SBP, DBP). Average egg intake (g/d) was calculated. Multivariable linear regression models were used to estimate the association between egg intake (per each 50 g/d or per quintile) and BP. The roles of dietary variables and other macro- and micro-nutrients in this association were also investigated.

settingIn the USA.

participantsIn total, 2195 US INTERMAP men and women aged 40-59 years.

resultsParticipants were 50 % female, 54 % non-Hispanic White and 16 % non-Hispanic Black. Mean egg intake (sd) in men and women was 30·4(29·8) and 21·6(20·5) g/d, respectively. Adjusting for demographics, socio-economics, lifestyle and urinary Na:K excretion ratios, we found non-linear associations with BP in non-obese women (P-quadratic terms: 0·004 for SBP and 0·035 for DBP).The associations remained after adjusting for dietary variables, macro/micro nutrients or minerals. Dietary cholesterol was highly correlated with egg intake and may factor in the association. No association was found in obese women and in obese or non-obese men.

conclusionEgg intake was non-linearly associated with SBP and DBP in non-obese women, but not in obese women or men. Underlying mechanisms require additional study regarding the role of obesity and sex.

Indexed as

HypertensionMicronutrientsAdultBlood PressureCross-Sectional StudiesDietFemaleHumansMaleMiddle AgedMicronutrientsBlood pressureDietEgg intakeHypertension

Identifiers

PMID34334150
PMCPMC11148583
OpenAlexW3192071350

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.