Evidence map›Paper›PMID 34337303›Full record

ArticleAnnals of gastroenterological surgery2021

Treatment of intrahepatic recurrence after hepatectomy for hepatocellular carcinoma.

Michinori Matsumoto, Katsuhiko Yanaga, Hiroaki Shiba, Shigeki Wakiyama, Taro Sakamoto, Yasuro Futagawa, Takeshi Gocho, Yuichi Ishida, Toru Ikegami

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michinori MatsumotoDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-5860-1103
Katsuhiko YanagaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0001-8918-4720
Hiroaki ShibaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-0688-2078
Shigeki WakiyamaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-0108-7657
Taro SakamotoDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-5917-7201
Yasuro FutagawaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0003-1994-6309
Takeshi GochoDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-8463-905X
Yuichi IshidaDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-8065-341X
Toru IkegamiDepartment of Surgery The Jikei University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0001-5792-5045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrognostic factors after treatment for intrahepatic recurrent hepatocellular carcinoma (RHCC) after hepatic resection (Hx) are controversial. The current study aimed to examine the impact of treatment modality on the prognosis of intrahepatic RHCC following Hx.

methodsFor control of variables, the subjects were 56 patients who underwent treatment for intrahepatic RHCC, three or fewer tumors, each measuring ≤3 cm in diameter without macroscopic vascular invasion (MVI), between 2000 and 2011. Retreatment consisted of repeat Hx (n = 23), local ablation therapy (n = 11) and transarterial chemoembolization or transcatheter arterial infusion (TACE/TAI) (n = 22). We retrospectively investigated the relation between type of treatment for RHCC and overall survival (OS) as well as disease-free survival (DFS).

resultsIn multivariate (MV) analysis, the poor prognostic factors in DFS after retreatment consisted of disease-free interval (DFI) (≤1.5 y) (

conclusionsDFI (≤1.5 y) was an independent poor prognostic factor in both DFS and OS, and repeat Hx for intrahepatic RHCC, few in number and size without MVI, seems to achieve the most reliable local control.

Indexed as

hepatectomyhepatocellular carcinomaradiofrequency ablationrecurrenceretreatment

Identifiers

PMID34337303
PMCPMC8316745

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.