Evidence map›Paper›PMID 34348482›Full record

ReviewAntioxidants & redox signaling2021

The MAVS Immune Recognition Pathway in Viral Infection and Sepsis.

Arjun Sharma, Konstantinos Kontodimas, Markus Bosmann

Open access · greenAbstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Review
  6. Review
  7. Article
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  12. Palmitoylation modulates antitumor immunity.Molecular biology reports · 2025
    Review
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  14. Review
  15. Article
  16. Review
  17. Article
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  20. Targeting PRMT7-mediated monomethylation of MAVS enhances antiviral innate immune responses and inhibits RNA virus replication.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Arjun SharmaPulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-5705-5470
Konstantinos KontodimasPulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Markus BosmannPulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0003-2773-1033
Boston University · US

Funding

Project-005UL1TR001430 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BAIR-MERRITT, MEGAN H, CENTER, DAVID M. · 2015 to 2024
$52.3M
Role reversal of MAVS in bacterial sepsisR01HL141513 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BOSMANN, MARKUS · 2018 to 2022
$2.4M
Bacterial polyphosphates in sepsisR01AI153613 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BOSMANN, MARKUS · 2021 to 2024
$2.1M
New genetic models for C5a receptorsR01HL139641 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BOSMANN, MARKUS · 2018 to 2022
$2.1M
NCATS NIH HHS UL1 TR001430NHLBI NIH HHS R01 HL139641NHLBI NIH HHS R01 HL141513NIAID NIH HHS R01 AI153613
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsHost-Pathogen InteractionsHumansImmune EvasionSepsisSignal TransductionVirus DiseasesAdaptor Proteins, Signal TransducingARDSCARDIFCOVID-19DDX58IFIH1IPS-1LGP2reactive oxygen speciesVISA

Identifiers

PMID34348482
PMCPMC8817698
OpenAlexW3191254859

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.