Evidence map›Paper›PMID 34349721›Full record

SynthesisFrontiers in neurology2021

Association Between Diabetes Medications and the Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis.

Xiaocui Qin, Xia Zhang, Pinyu Li, Min Wang, Li Yan, Zeqing Bao, Qili Liu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Exploring the impacts of type 2 diabetes and metformin use on Parkinson's disease: Mendelian randomization analysis and a national cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Review
  7. Insulin Resistance Is a Modifying Factor for Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025
    Article
  8. Metabolic Parkinson's disease.Frontiers in aging neuroscience · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Novel and experimental therapeutics for the management of motor and non-motor Parkinsonian symptoms.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  13. The Contribution of Type 2 Diabetes to Parkinson's Disease Aetiology.International journal of molecular sciences · 2024
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Annals of nuclear medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaocui QinDepartment of Physiology, Zhaoqing Medical College, Zhaoqing, China.
Xia ZhangDepartment of Pathology and Physiology, Zhaoqing Medical College, Zhaoqing, China.
Pinyu LiDepartment of Pathology and Physiology, Zhaoqing Medical College, Zhaoqing, China.
Min WangDepartment of Pathology and Physiology, Zhaoqing Medical College, Zhaoqing, China.
Li YanDepartment of Pharmacology, Zhaoqing Medical College, Zhaoqing, China.
Zeqing BaoDepartment of Pharmacology, Zhaoqing Medical College, Zhaoqing, China.
Qili LiuDepartment of Physiology, Zhaoqing Medical College, Zhaoqing, China.
Zhaoqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dipeptidyl peptidase-4 inhibitorsglitazonesglucagon-like peptide-1 agonistsmetforminsulfonylureas

Identifiers

PMID34349721
PMCPMC8326375
OpenAlexW3185370606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.