Evidence map›Paper›PMID 34356937›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Profile of Membrane Cargo Trafficking Proteins and Transporters Expressed under N Source Derepressing Conditions in

Sofia Dimou, Xenia Georgiou, Eleana Sarantidi, George Diallinas, Athanasios K Anagnostopoulos

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sofia DimouDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, 15784 Athens, Greece.
Xenia GeorgiouDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, 15784 Athens, Greece.
Eleana SarantidiDivision of Biotechnology, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.
George DiallinasDepartment of Biology, National and Kapodistrian University of Athens, Panepistimioupolis, 15784 Athens, Greece.ORCID 0000-0002-3426-726X
Athanasios K AnagnostopoulosDivision of Biotechnology, Biomedical Research Foundation of the Academy of Athens (BRFAA), 11527 Athens, Greece.ORCID 0000-0001-5161-7850
National and Kapodistrian University of Athens · GRBiomedical Research Foundation of the Academy of Athens · GR

Funding

Fondation Santé ELKE KE17237
6 · The paper itself

Abstract

Solute and ion transporters are proteins essential for cell nutrition, detoxification, signaling, homeostasis and drug resistance. Being polytopic transmembrane proteins, they are co-translationally inserted and folded into the endoplasmic reticulum (ER) of eukaryotic cells and subsequently sorted to their final membrane destination via vesicular secretion. During their trafficking and in response to physiological/stress signals or prolonged activity, transporters undergo multiple quality control processes and regulated turnover. Consequently, transporters interact dynamically and transiently with multiple proteins. To further dissect the trafficking and turnover mechanisms underlying transporter subcellular biology, we herein describe a novel mass spectrometry-based proteomic protocol adapted to conditions allowing for maximal identification of proteins related to N source uptake in

Indexed as

A. nidulansfunginutrient transportersproteomesecretionturnover

Identifiers

PMID34356937
PMCPMC8306328
OpenAlexW3181479301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.