Evidence map›Paper›PMID 34360812›Full record

ReviewInternational journal of molecular sciences2021

A Review of the Neutrophil Extracellular Traps (NETs) from Cow, Sheep and Goat Models.

Mulumebet Worku, Djaafar Rehrah, Hamid D Ismail, Emmanuel Asiamah, Sarah Adjei-Fremah

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. The CAMKK/AMPK Pathway Contributes toInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in immunology · 2023
    Article
  7. Review
  8. Article
  9. Taurine inhibitsFrontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mulumebet WorkuDepartment of Animal Sciences, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, NC 27411, USA.ORCID 0000-0003-3663-4745
Djaafar RehrahDepartment of Animal Sciences, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, NC 27411, USA.
Hamid D IsmailDepartment of Animal Sciences, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, NC 27411, USA.
Emmanuel AsiamahDepartment of Agriculture, University of Arkansas at Pine Bluff, 1200 N. University Drive, Mail Slot 4913, Pine Bluff, AR 71601, USA.
Sarah Adjei-FremahResearch & Economic Development, North Carolina Agricultural and Technical State University, 1601 East Market Street, Greensboro, NC 27411, USA.ORCID 0000-0001-6198-7097
North Carolina Agricultural and Technical State University · USUniversity of Arkansas at Pine Bluff · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review provides insight into the importance of understanding NETosis in cows, sheep, and goats in light of the importance to their health, welfare and use as animal models. Neutrophils are essential to innate immunity, pathogen infection, and inflammatory diseases. The relevance of NETosis as a conserved innate immune response mechanism and the translational implications for public health are presented. Increased understanding of NETosis in ruminants will contribute to the prediction of pathologies and design of strategic interventions targeting NETs. This will help to control pathogens such as coronaviruses and inflammatory diseases such as mastitis that impact all mammals, including humans. Definition of unique attributes of NETosis in ruminants, in comparison to what has been observed in humans, has significant translational implications for one health and global food security, and thus warrants further study.

Indexed as

Immunity, InnateAnimalsExtracellular TrapsHumansNeutrophilsRuminantshealthhumansneutrophil extracellular traps NETsneutrophilspathogensruminantstherapy

Identifiers

PMID34360812
PMCPMC8347029
OpenAlexW3186676627

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.