Evidence map›Paper›PMID 34360869›Full record

ArticleInternational journal of molecular sciences2021

Characterization of the Intramolecular Interactions and Regulatory Mechanisms of the Scaffold Protein Tks4.

Balázs Merő, Kitti Koprivanacz, Anna Cserkaszky, László Radnai, Virag Vas, Gyöngyi Kudlik, Gergő Gógl, Péter Sok, Ádám L Póti, Bálint Szeder and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Balázs MerőResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.ORCID 0000-0001-9517-6460
Kitti KoprivanaczResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.
Anna CserkaszkyResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.
László RadnaiResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.ORCID 0000-0001-6843-3740
Virag VasResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.ORCID 0000-0001-7249-6816
Gyöngyi KudlikResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.ORCID 0000-0002-2210-7410
Gergő GóglDepartment of Biochemistry, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0002-8597-3711
Péter SokResearch Centre for Natural Sciences, Institute of Organic Chemistry, 1117 Budapest, Hungary.ORCID 0000-0001-8963-8163
Ádám L PótiResearch Centre for Natural Sciences, Institute of Organic Chemistry, 1117 Budapest, Hungary.
Bálint SzederResearch Centre for Natural Sciences, Institute of Enzymology, 1117 Budapest, Hungary.ORCID 0000-0003-3264-3900
László NyitrayDepartment of Biochemistry, Eötvös Loránd University, 1117 Budapest, Hungary.
Attila ReményiResearch Centre for Natural Sciences, Institute of Organic Chemistry, 1117 Budapest, Hungary.ORCID 0000-0002-8345-1311
Miklós GeisztDepartment of Physiology, Semmelweis University, 1094 Budapest, Hungary.
László BudayDepartment of Biochemistry, Eötvös Loránd University, 1117 Budapest, Hungary.ORCID 0000-0003-3518-5757
Institute of Molecular Life Sciences · HUInstitute of Organic Chemistry · HUEötvös Loránd University · HUSemmelweis University · HU

Funding

Magyarország Kormánya K124045, FIEK_16-1-2016-0005, HunProtEx 2018-1.2.1-NKP-2018-00005, VEKOP-2.3.3.5-15-2016-00011, K119359
6 · The paper itself

Abstract

The scaffold protein Tks4 is a member of the p47

Indexed as

Adaptor Proteins, Signal TransducingBinding SitesHumansModels, MolecularPhosphatidylinositol PhosphatesProline-Rich Protein DomainsProtein Bindingsrc Homology DomainsAdaptor Proteins, Signal Transducingphosphatidylinositol 3-phosphatePhosphatidylinositol PhosphatesSH3PXD2B protein, humanautoinhibited conformationITClipid bindingMSTp47PtdIns(3)PPX domainSAXSscaffold proteinsSH3 domaintandem SH3Tks4Tks5

Identifiers

PMID34360869
PMCPMC8348221
OpenAlexW3184600546

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.