Evidence map›Paper›PMID 34361048›Full record

ReviewInternational journal of molecular sciences2021

Phytochemicals in Malignant Pleural Mesothelioma Treatment-Review on the Current Trends of Therapies.

Malgorzata Chmielewska-Kassassir, Lucyna A Wozniak

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Identification of Cembrane Diterpenoids fromJournal of natural products · 2025
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Malgorzata Chmielewska-KassassirDepartment of Structural Biology, Medical University of Lodz, Zeligowskiego 7/9 Str., 90-752 Lodz, Poland.ORCID 0000-0003-1440-2222
Lucyna A WozniakDepartment of Structural Biology, Medical University of Lodz, Zeligowskiego 7/9 Str., 90-752 Lodz, Poland.ORCID 0000-0002-9966-1807

Funding

Narodowym Centrum Nauki 2015/19/N/NZ3/01497
6 · The paper itself

Abstract

Malignant pleural mesothelioma (MPM) is a rare but highly aggressive tumor of pleura arising in response to asbestos fibers exposure. MPM is frequently diagnosed in the advanced stage of the disease and causes poor prognostic outcomes. From the clinical perspective, MPM is resistant to conventional treatment, thus challenging the therapeutic options. There is still demand for improvement and sensitization of MPM cells to therapy in light of intensive clinical studies on chemotherapeutic drugs, including immuno-modulatory and targeted therapies. One way is looking for natural sources, whole plants, and extracts whose ingredients, especially polyphenols, have potential anticancer properties. This comprehensive review summarizes the current studies on natural compounds and plant extracts in developing new treatment strategies for MPM.

Indexed as

AnimalsAntineoplastic Agents, PhytogenicBiological ProductsHumansMesothelioma, MalignantPolyphenolsAntineoplastic Agents, PhytogenicBiological ProductsPolyphenolschemotherapyMPMnatural compoundsphytochemicalspolyphenols

Identifiers

PMID34361048
PMCPMC8348618

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.