ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2022
Raman needle arthroscopy for in vivo molecular assessment of cartilage.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The trial behind it
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Multimodal characterization of articular cartilage degeneration in the humeral head using Raman spectroscopy, biomechanics, and imaging.Osteoarthritis and cartilage · 2026Article
- Histopathological analysis for human articular cartilage using a Raman probe system.Journal of biomedical optics · 2026Article
- Application and benefit analysis of needle arthroscopy for joint disease diagnosis and treatment.iScience · 2026Review
- Assessing the micromechanical architecture of joint tissues with speckle rheological microscopy.Nature communications · 2026Article
- A sulfonated cartilage interpenetrating polymer network reinforces and protects the extracellular matrix of degraded cartilage.Acta biomaterialia · 2026Article
- Evaluation of Engineered Cartilage Composition and Function Using Raman Spectroscopy.Advanced healthcare materials · 2025Article
- Rotator Cuff Tear-induced Changes in Tendon Structure and Mechanics Measured by Quantitative Magnetic Resonance Imaging.Annals of biomedical engineering · 2025Article
- Open Raman Microscopy (ORM): A Modular Hardware and Software Framework for Accessible Raman Imaging.bioRxiv : the preprint server for biology · 2025Article
- Time-resolved Raman spectroscopy using a CMOS SPAD array to remove fluorescent and fibre Raman backgrounds.Biomedical optics express · 2025Article
- Evaluation method for proteoglycans using near-infrared spectroscopy.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Raman spectroscopic probe provides optical biomarkers of cartilage composition predictive of tissue function.Osteoarthritis and cartilage · 2025Article
- Label-free 3D molecular imaging of living tissues using Raman spectral projection tomography.Nature communications · 2024Article
- Arterial Blood Supply of the Stifle Joint in Horses.Animals : an open access journal from MDPI · 2024Article
- Ultraviolet-Visible-Near Infrared Spectroscopy May Aid in the Qualitative Assessment of Early-Stage Cartilage Degradation.Arthroscopy, sports medicine, and rehabilitation · 2024Article
- Raman Spectroscopy and Machine Learning Enables Estimation of Articular Cartilage Structural, Compositional, and Functional Properties.Annals of biomedical engineering · 2023Article
- Practices, Potential, and Perspectives for Detecting Predisease Using Raman Spectroscopy.International journal of molecular sciences · 2023Review
- Prognostic potential and pathological validation of a diagnostic application using Raman spectroscopy in the characterization of degenerative changes in the cartilage of the humeral head.Journal of biomedical optics · 2022Article
- Raman needle arthroscopy for in vivo molecular assessment of cartilage.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of treatments for osteoarthritis (OA) is burdened by the lack of standardized biomarkers of cartilage health that can be applied in clinical trials. We present a novel arthroscopic Raman probe that can "optically biopsy" cartilage and quantify key extracellular matrix (ECM) biomarkers for determining cartilage composition, structure, and material properties in health and disease. Technological and analytical innovations to optimize Raman analysis include (1) multivariate decomposition of cartilage Raman spectra into ECM-constituent-specific biomarkers (glycosaminoglycan [GAG], collagen [COL], water [H
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.