Evidence map›Paper›PMID 34376173›Full record

ArticleBMC infectious diseases2021

Clinic-based diabetes screening at the time of HIV testing and associations with poor clinical outcomes in South Africa: a cohort study.

Rachel W Kubiak, Mario Kratz, Ayesha A Motala, Sean Galagan, Sabina Govere, Elisabeth R Brown, Mahomed-Yunus S Moosa, Paul K Drain

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rachel W KubiakDepartment of Epidemiology, Health Sciences Building, University of Washington, Seattle, WA, USA. rwkubiak@uw.edu.ORCID http://orcid.org/0000-0002-2315-4112
Mario KratzDepartment of Epidemiology, Health Sciences Building, University of Washington, Seattle, WA, USA.
Ayesha A MotalaDepartment of Diabetes and Endocrinology, University of KwaZulu-Natal, Durban, South Africa.
Sean GalaganDepartment of Global Health, University of Washington, Seattle, WA, USA.
Sabina GovereAIDS Healthcare Foundation, Durban, South Africa.
Elisabeth R BrownStatistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Mahomed-Yunus S MoosaDepartment of Infectious Diseases, University of KwaZulu-Natal, Durban, South Africa.
Paul K DrainDepartment of Epidemiology, Health Sciences Building, University of Washington, Seattle, WA, USA.
University of Washington · USUniversity of KwaZulu-Natal · ZAAIDS Healthcare Foundation · ZA

Funding

Clinic-based Screening to Prevent HIV-associated Cryptococcal MortalityK23AI108293 · NIAID · UNIVERSITY OF WASHINGTON · PI DRAIN, PAUL K · 2014 to 2018
$928k
Advancing point-of-care diagnostics for integrated HIV and TB care in South AfricaR03AI143351 · NIAID · UNIVERSITY OF WASHINGTON · PI DRAIN, PAUL K · 2019 to 2020
$145k
The impact of diabetes on tuberculosis incidence and mortality in HIV-positive adultsF31AI138633 · NIAID · UNIVERSITY OF WASHINGTON · PI KUBIAK, RACHEL WENGER · 2019 to 2020
$68k
NIAID NIH HHS F31 AI138633NIAID NIH HHS K23 AI108293NIAID NIH HHS R03 AI143351
6 · The paper itself

Abstract

backgroundHIV clinical care programs in high burden settings are uniquely positioned to facilitate diabetes diagnosis, which is a major challenge. However, in sub-Saharan Africa, data on the burden of diabetes among people living with HIV (PLHIV) and its impact on HIV outcomes is sparse.

methodsWe enrolled adults presenting for HIV testing at an outpatient clinic in Durban. Those who tested positive for HIV-infection were screened for diabetes using a point-of-care hemoglobin A

resultsAmong 1369 PLHIV, 0.5% (n = 7) reported a prior diabetes diagnosis, 20.6% (95% CI 18.5-22.8%, n = 282) screened positive for pre-diabetes (HbA

conclusionsDiabetes and pre-diabetes were common among adults testing positive for HIV and associated with death. Clinic-based diabetes screening could be targeted to higher risk groups and may improve HIV treatment outcomes.

Indexed as

Anti-HIV AgentsDiabetes MellitusHIV InfectionsAdultAmbulatory Care FacilitiesCohort StudiesHIV TestingHumansSouth AfricaAnti-HIV AgentsDiabetes mellitusHIVHyperglycemiaMortalityPre-diabetesTuberculosis

Identifiers

PMID34376173
PMCPMC8353828
OpenAlexW3192949887

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.