Evidence map›Paper›PMID 34379213›Full record

ReviewWorld journal of microbiology & biotechnology2021

Cytolethal distending toxin: from genotoxin to a potential biomarker and anti-tumor target.

Swadha Kailoo, Shreya, Yatender Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Genomic profiling of enterotoxigenicMicrobial genomics · 2025
    Article
  2. Journal of translational autoimmunity · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Swadha KailooDepartment of Biological Sciences & Engineering, Netaji Subhas University of Technology (NSUT), Formerly Netaji Subhas Institute of Technology (NSIT), Azad Hind Fauz Marg, Dwarka Sector-3, New Delhi, 110078, India.
ShreyaDepartment of Biological Sciences & Engineering, Netaji Subhas University of Technology (NSUT), Formerly Netaji Subhas Institute of Technology (NSIT), Azad Hind Fauz Marg, Dwarka Sector-3, New Delhi, 110078, India.
Yatender KumarDepartment of Biological Sciences & Engineering, Netaji Subhas University of Technology (NSUT), Formerly Netaji Subhas Institute of Technology (NSIT), Azad Hind Fauz Marg, Dwarka Sector-3, New Delhi, 110078, India. yatender.kumar@nsut.ac.in.ORCID http://orcid.org/0000-0002-9835-9892
Netaji Subhas University of Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytolethal Distending Toxin (CDT) belongs to the AB toxin family and is produced by a plethora of Gram-negative bacteria. Eight human-affecting enteropathogens harbor CDT that causes irritable bowel syndrome (IBS), dysentery, chancroid, and periodontitis worldwide. They have a novel molecular mode of action as they interfere in the eukaryotic cell-cycle progression leading to G

Indexed as

Antineoplastic AgentsBacterial ToxinsCell CycleGram-Negative BacteriaHumansModels, MolecularMutagensOperonProtein ConformationAntineoplastic AgentsBacterial Toxinscytolethal distending toxinMutagensAB toxinApoptosisCDTCellular distentionG2/M arrestVirulence

Identifiers

PMID34379213
OpenAlexW3188021939

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.