Evidence map›Paper›PMID 34383559›Full record

ArticleCirculation research2021

Dach1 Extends Artery Networks and Protects Against Cardiac Injury.

Brian Raftrey, Ian Williams, Pamela E Rios Coronado, Xiaochen Fan, Andrew H Chang, Mingming Zhao, Robert Roth, Emily Trimm, Raquel Racelis, Gaetano D'Amato and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
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  13. Review
  14. Article
  15. Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis andInternational journal of molecular sciences · 2024
    Article
  16. Article
  17. Epicardium and Coronary Vessels.Advances in experimental medicine and biology · 2024
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 3 countries.

Brian RaftreyDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Ian WilliamsDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0003-2906-8116
Pamela E Rios CoronadoDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Xiaochen FanDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0002-4316-0616
Andrew H ChangDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0002-4037-9831
Mingming ZhaoDivision of Pediatric Cardiology, Department of Pediatrics (M.Z., D.B.), Stanford University School of Medicine, CA.
Robert RothDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0001-9714-4745
Emily TrimmDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0001-8610-3075
Raquel RacelisDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Gaetano D'AmatoDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Ragini PhansalkarDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Alana NguyenInstitute for Stem Cell Biology and Regenerative Medicine (A.N., T.C., K.M.G., L.T.A., K.L., K.R.-H.), Stanford University School of Medicine, CA.ORCID 0000-0002-3413-1987
Timothy ChaiInstitute for Stem Cell Biology and Regenerative Medicine (A.N., T.C., K.M.G., L.T.A., K.L., K.R.-H.), Stanford University School of Medicine, CA.ORCID 0000-0001-6258-066X
Karen M GonzalezDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).
Yue ZhangDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0002-2955-7780
Lay Teng AngInstitute for Stem Cell Biology and Regenerative Medicine (A.N., T.C., K.M.G., L.T.A., K.L., K.R.-H.), Stanford University School of Medicine, CA.
Kyle M LohInstitute for Stem Cell Biology and Regenerative Medicine (A.N., T.C., K.M.G., L.T.A., K.L., K.R.-H.), Stanford University School of Medicine, CA.
Daniel BernsteinDivision of Pediatric Cardiology, Department of Pediatrics (M.Z., D.B.), Stanford University School of Medicine, CA.
Kristy Red-HorseDepartment of Biology, Stanford University, CA (B.R., I.W., P.E.R.C., X.F., A.H.C., R. Roth, E.T., R. Racelis, G.D., R.P., K.M.G., Y.Z., K.R.-H.).ORCID 0000-0003-1541-601X
Stanford University · USInstitute for Stem Cell Biology and Regenerative Medicine · INCardiovascular Institute of the South · USRoth and Rau (Germany) · DE

Funding

Supplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9M
T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Mechanotransduction and transcriptional regulation during artery developmentR01HL128503 · NHLBI · STANFORD UNIVERSITY · PI Mary Red-Horse · 2015 to 2026
$5.8M
Endothelial-pericyte interactions in the pathogenesis of pulmonary arterial hypertensionR01HL139664 · NHLBI · STANFORD UNIVERSITY · PI DE JESUS PEREZ, VINICIO A · 2018 to 2025
$4.7M
Program in Translational and Experimental HematologyT32HL120824 · NHLBI · STANFORD UNIVERSITY · PI MAJETI, RAVINDRA · 2014 to 2023
$2.4M
Developing approaches for universal organ transplantationDP5OD024558 · OD · STANFORD UNIVERSITY · PI LOH, KYLE M · 2017 to 2021
$2.0M
Stanford Undergraduate URM Summer Cardiovascular Research ProgramR25HL147666 · NHLBI · STANFORD UNIVERSITY · PI VINICIO A DE JESUS PEREZ, Mary Red-Horse · 2019 to 2026
$1.0M
High-throughput sequencer for multi-scale genomic studiesS10OD020141 · OD · STANFORD UNIVERSITY · PI SNYDER, MICHAEL P. · 2015 to 2015
$600k
Investigating the Role of Dach1 in Artery Specification and Collateral Artery DevelopmentF31HL147410 · NHLBI · STANFORD UNIVERSITY · PI RAFTREY, BRIAN CHRISTOPHER · 2019 to 2020
$68k
NHLBI NIH HHS F31 HL147410NHLBI NIH HHS R01 HL128503NHLBI NIH HHS R01 HL139664NHLBI NIH HHS R25 HL147666NHLBI NIH HHS T32 HL098049NHLBI NIH HHS T32 HL120824NIGMS NIH HHS T32 GM007276NIH HHS DP5 OD024558NIH HHS S10 OD020141
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsCell DifferentiationCoronary Artery DiseaseCoronary VesselsEndothelium, VascularEye ProteinsGain of Function MutationLipid MetabolismMiceMice, Inbred C57BLMyocardiumNeovascularization, PhysiologicDach1 protein, mouseEye Proteinscell differentiationcoronary artery diseaseendothelial cellsmyocardial infarctionretina

Identifiers

PMID34383559
PMCPMC8448957
OpenAlexW3189262009

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.