Evidence map›Paper›PMID 34386103›Full record

ReviewBeilstein journal of organic chemistry2021

On the application of 3d metals for C-H activation toward bioactive compounds: The key step for the synthesis of silver bullets.

Renato L Carvalho, Amanda S de Miranda, Mateus P Nunes, Roberto S Gomes, Guilherme A M Jardim, Eufrânio N da Silva Júnior

Open access · diamondAbstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Earth-abundant 3d transition metals on the rise in catalysis.Beilstein journal of organic chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Renato L CarvalhoInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais - UFMG, CEP 31270-901, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-8515-9306
Amanda S de MirandaInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais - UFMG, CEP 31270-901, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-8887-2772
Mateus P NunesInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais - UFMG, CEP 31270-901, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0003-4796-3448
Roberto S GomesDepartment of Pharmaceutical Sciences, North Dakota State University, Fargo, ND, United States.ORCID https://orcid.org/0000-0002-8075-9716
Guilherme A M JardimInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais - UFMG, CEP 31270-901, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0002-9882-3085
Eufrânio N da Silva JúniorInstitute of Exact Sciences, Department of Chemistry, Federal University of Minas Gerais - UFMG, CEP 31270-901, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0003-1281-5453
Universidade Federal de Minas Gerais · BRNorth Dakota State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several valuable biologically active molecules can be obtained through C-H activation processes. However, the use of expensive and not readily accessible catalysts complicates the process of pharmacological application of these compounds. A plausible way to overcome this issue is developing and using cheaper, more accessible, and equally effective catalysts. First-row transition (3d) metals have shown to be important catalysts in this matter. This review summarizes the use of 3d metal catalysts in C-H activation processes to obtain potentially (or proved) biologically active compounds.

Indexed as

3d metalsbioactive compoundsC–H activationdrugsmedicinal chemistry

Identifiers

PMID34386103
PMCPMC8329403
OpenAlexW3188482424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.