Evidence map›Paper›PMID 34387718›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2022

Quantifying cardiac sympathetic denervation: first studies of

David M Raffel, Thomas C Crawford, Yong-Woon Jung, Robert A Koeppe, Guie Gu, Jill Rothley, Kirk A Frey

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02669563 (An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02669563 early_phase1completednot on this map

An Exploratory Study of 18F-Labeled Hydroxyphenethylguanidines in Heart Failure Patients

TypeinterventionalSponsorUniversity of MichiganRan2015 to 2016Enrolled16ConditionsCardiomyopathyArms[18F]4F-MHPG, [18F]3F-PHPG, [13N]ammonia, [11C]HED
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Modified Reaction Conditions for the Radiosynthesis ofACS medicinal chemistry letters · 2026
    Article
  2. Review
  3. Review
  4. 3-[Journal of the Endocrine Society · 2024
    Article
  5. Sympathetic Nervous System and Atherosclerosis.International journal of molecular sciences · 2023
    Review
  6. Article
  7. PET imaging of metastatic paraganglioma using novel 3-[European journal of nuclear medicine and molecular imaging · 2022
    Article
  8. Nerve regeneration in transplanted organs and tracer imaging studies: A review.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

David M RaffelDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA. raffel@umich.edu.ORCID http://orcid.org/0000-0002-7188-9463
Thomas C CrawfordDivision of Cardiology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, 48109, USA.
Yong-Woon JungDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA.
Robert A KoeppeDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA.
Guie GuDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA.
Jill RothleyDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA.
Kirk A FreyDivision of Nuclear Medicine, Department of Radiology, University of Michigan Medical School, 2276 Medical Science I, 1301 Catherine St., Ann Arbor, MI, 48109-5610, USA.
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose4-

methodsEight cardiomyopathy patients were scanned with

resultsPatlak analysis of

conclusionThe advantages of

trial registrationRegistered at the ClinicalTrials.gov website (NCT02669563). URL: https://clinicaltrials.gov/ct2/show/NCT02669563.

Indexed as

CardiomyopathiesPositron-Emission TomographyHeartHumansKineticsSympathectomySympathetic Nervous SystemArrhythmiaSudden cardiac deathSympathetic nervous system

Identifiers

PMID34387718
OpenAlexW3163231329

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.