Evidence mapPaperPMID 34395635Full record

ArticleJournal of immunology research2021

Inflamm-Aging-Related Cytokines of IL-17 and IFN-

Jingyi Tan, Anna Dai, Lai Pan, Lan Zhang, Zhongxiu Wang, Ting Ke, Weilian Sun, Yanmin Wu, Pei-Hui Ding, Lili Chen

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. The Role of Cytokines in Orthodontic Tooth Movement.International journal of molecular sciences · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Association between periodontal disease and prostate disease: a mini review.Frontiers in cellular and infection microbiology · 2025
    Review
  17. CRISPRJournal of oral microbiology · 2025
    Article
  18. Article
  19. Article
  20. Everolimus alleviates CD4GeroScience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jingyi Tan *Department of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Anna Dai *Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, Zhejiang 310006, China.
Lai PanDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Lan ZhangStomatology Department, Zhejiang Hospital, Hangzhou 310007, China.
Zhongxiu WangDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Ting KeDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Weilian SunDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Yanmin WuDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.
Pei-Hui DingStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Clinical Research Center for Oral Diseases of Zhejiang Province, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, Zhejiang 310006, China.ORCID https://orcid.org/0000-0001-6147-1787
Lili ChenDepartment of Periodontology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China.ORCID https://orcid.org/0000-0002-0620-8844
Second Affiliated Hospital of Zhejiang University · CNStomatology Hospital · CNZhejiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease (PD), as an age-related disease, prevalent in middle-aged and elderly population, is characterized as inflammatory periodontal tissue loss, including gingival inflammation and alveolar bone resorption. However, the definite mechanism of aging-related inflammation in PD pathology needs further investigation. Our study is aimed at exploring the effect of inflamm-aging-related cytokines of interleukin-17 (IL-17) and interferon-

Indexed as

OsteogenesisAgingAnimalsBiomarkersCell DifferentiationCytokinesDisease SusceptibilityGene ExpressionImmunohistochemistryInflammation MediatorsInterferon-gammaInterleukin-17MacrophagesMiceOrgan SpecificityOsteoclastsBiomarkersCytokinesInflammation MediatorsInterferon-gammaInterleukin-17

Identifiers

PMID34395635
PMCPMC8357511
OpenAlexW3192439014

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.