Evidence map›Paper›PMID 34403124›Full record

ArticleJournal of racial and ethnic health disparities2022

Racial Differences in the Effect of HIV Status on Motor and Pulmonary Function and Mobility Disability in Older Adults.

Brittney S Lange-Maia, Aron S Buchman, Sue E Leurgans, Melissa Lamar, Elizabeth B Lynch, Kristine M Erlandson, Lisa L Barnes

Open access · greenAbstract read
In one paragraph

Article in Journal of racial and ethnic health disparities, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Brittney S Lange-MaiaRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA. Brittney_Lange-Maia@Rush.edu.ORCID http://orcid.org/0000-0001-6642-7558
Aron S BuchmanRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Melissa LamarRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Elizabeth B LynchDepartment of Preventive Medicine, Rush University Medical Center, Chicago, IL, USA.
Kristine M ErlandsonDepartment of Medicine and Epidemiology, University of Colorado Anschutz Medical Center, Aurora, CO, USA.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Rush University Medical Center · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Rush Center of Excellence on Disparties in HIV and Aging (CEDHA)P20MD006886 · NIMHD · RUSH UNIVERSITY MEDICAL CENTER · PI SHAH, RAJ C · 2012 to 2016
$6.0M
The High-Intensity Exercise to Attenuate Limitations and Train Habits (HEALTH) in Older Adults with HIVR01AG066562 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE, WEBEL, ALLISON R · 2020 to 2024
$4.3M
NIA NIH HHS R01 AG066562NIMHD NIH HHS P20 MD006886
6 · The paper itself

Abstract

backgroundOlder Black adults face a disproportionate burden of HIV prevalence, but less is known about racial disparities in age-related outcomes in HIV. We assessed the effect of HIV status and race on motor and pulmonary function, as well as how they contribute to mobility disability.

settingCommunity-based study; Chicago, IL

methodsParticipants were 363 community-dwelling adults age ≥ 50 years, 48% living with HIV, and 68% Black. Participants with HIV were recruited from a specialty HIV clinic, and participants without HIV (comparable on key demographic, lifestyle, and behavioral characteristics) were recruited from the community. Measures included motor function summarized by 10 motor performance measures, pulmonary function summarized by 3 measures assessed using handheld spirometry, and self-reported mobility disability.

resultsIn fully adjusted linear models, HIV was associated with better motor (β = 9.35, p < 0.001) and pulmonary function (β = 16.34, p < 0.001). For pulmonary function, the effect of HIV status was moderated by race (interaction between Black race and HIV status: β =  - 11.66, p = 0.02), indicating that better pulmonary function among participants with HIV was less evident among Black participants. In fully adjusted models, odds of mobility disability did not differ by race, HIV status, or pulmonary function; better motor function was associated with lower odds of mobility disability (OR = 0.91 per 1-point higher, 95% CI 0.88-0.93).

conclusionBetter motor and pulmonary function exhibited by participants with HIV could reflect access to medical care. Racial differences in lung function among participants with HIV indicate potential disparities in prevention or treatment of pulmonary disease or underlying risk factors.

Indexed as

HIV InfectionsPersons with DisabilitiesAgedHumansLungMiddle AgedRace FactorsRisk FactorsAgingHealth disparitiesHIV/AIDSMobility

Identifiers

PMID34403124
PMCPMC8850535
OpenAlexW3196277880

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.