Evidence map›Paper›PMID 34421687›Full record

ReviewFrontiers in psychiatry2021

Nutrition, Gut Microbiota, and Alzheimer's Disease.

Mariana Romanenko, Victor Kholin, Alexander Koliada, Alexander Vaiserman

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Host insulin resistance caused byFrontiers in cellular and infection microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mariana RomanenkoLaboratory of Dietetics, D.F. Chebotarev State Institute of Gerontology NAMS of Ukraine, Kyiv, Ukraine.
Victor KholinDepartment of Age Physiology and Pathology of the Nervous System, D.F. Chebotarev State Institute of Gerontology NAMS of Ukraine, Kyiv, Ukraine.
Alexander KoliadaMolecular Genetic Laboratory Diagen, Kyiv, Ukraine.
Alexander VaisermanLaboratory of Epigenetics, D.F. Chebotarev State Institute of Gerontology NAMS of Ukraine, Kyiv, Ukraine.
D.F. Chebotarev Institute of Gerontology · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrition is known to play an important role in the pathogenesis of Alzheimer's disease. Evidence is obtained that the gut microbiota is a key player in these processes. Dietary changes (both adverse and beneficial) may influence the microbiome composition, thereby affecting the gut-brain axis and the subsequent risk for Alzheimer's disease progression. In this review, the research findings that support the role of intestinal microbiota in connection between nutritional factors and the risk for Alzheimer's disease onset and progression are summarized. The mechanisms potentially involved in these processes as well as the potential of probiotics and prebiotics in therapeutic modulation of contributed pathways are discussed.

Indexed as

Alzheimer's diseasecognitive functiondementiagut microbiotanutrition

Identifiers

PMID34421687
PMCPMC8374099
OpenAlexW3188826759

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.