Evidence map›Paper›PMID 34425796›Full record

ArticleBMC musculoskeletal disorders2021

Associations of overweight, obesity and osteoporosis with ankle fractures.

Anja M Hjelle, Ellen M Apalset, Jan-Erik Gjertsen, Roy M Nilsen, Anja Lober, Grethe S Tell, Pawel F Mielnik

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Ankle fractures: a pragmatic opportunity for osteoporosis case finding.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  4. Article
  5. Should we consider ankle fractures as osteoporotic fractures?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  6. Management of Geriatric Ankle Fractures.Current osteoporosis reports · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anja M HjelleDepartment of Rheumatology, Division of Medicine, District General Hospital of Førde, Førde, Norway. anja.myhre.hjelle@helse-forde.no.
Ellen M ApalsetDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Jan-Erik GjertsenDepartment of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway.
Roy M NilsenFaculty of Health and Social Sciences, Western Norway University of Applied Sciences, Bergen, Norway.
Anja LoberDepartment of Radiology, District General Hospital of Førde, Førde, Norway.
Grethe S TellDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Pawel F MielnikDepartment of Rheumatology, Division of Medicine, District General Hospital of Førde, Førde, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies exploring risk factors for ankle fractures in adults are scarce, and with diverging conclusions. This study aims to investigate whether overweight, obesity and osteoporosis may be identified as risk factors for ankle fractures and ankle fracture subgroups according to the Danis-Weber (D-W) classification.

methods108 patients ≥40 years with fracture of the lateral malleolus were included. Controls were 199 persons without a previous fracture history. Bone mineral density of the hips and spine was measured by dual-energy x-ray absorptiometry, and history of previous fracture, comorbidities, medication, physical activity, smoking habits, body mass index and nutritional factors were registered.

resultsHigher body mass index with increments of 5 gave an adjusted odds ratio (OR) of 1.30 (95% confidence interval (CI) 1.03-1.64) for ankle fracture, and an adjusted OR of 1.96 (CI 0.99-4.41) for sustaining a D-W type B or C fracture compared to type A. Compared to patients with normal bone mineral density, the odds of ankle fracture in patients with osteoporosis was 1.53, but the 95% CI was wide (0.79-2.98). Patients with osteoporosis had reduced odds of sustaining a D-W fracture type B or C compared to type A (OR 0.18, CI 0.03-0.83).

conclusionsOverweight increased the odds of ankle fractures and the odds of sustaining an ankle fracture with possible syndesmosis disruption and instability (D-W fracture type B or C) compared to the stable and more distal fibula fracture (D-W type A). Osteoporosis did not significantly increase the odds of ankle fractures, thus suffering an ankle fracture does not automatically warrant further osteoporosis assessment.

Indexed as

Ankle FracturesOsteoporosisAbsorptiometry, PhotonAdultBone DensityHumansObesityAnkle fractureDanis-weber classificationOsteoporosisOverweight

Identifiers

PMID34425796
PMCPMC8381556

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.