Evidence map›Paper›PMID 34434540›Full record

ArticleTherapeutic advances in chronic disease2021

A meta-analysis of granulocyte-macrophage colony-stimulating factor (GM-CSF) antibody treatment for COVID-19 patients.

Jin-Tao Guan, Wei-Jie Wang, Du Jin, Xiao-Yue Mou, Shan-Shan Lei, Zheng-Hao Xu

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Therapeutic advances in chronic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin-Tao GuanThe First People's Hospital of Taizhou, Zhejiang, China.
Wei-Jie WangThe Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Du JinThe First People's Hospital of Taizhou, Zhejiang, China.
Xiao-Yue MouThe First People's Hospital of Taizhou, Zhejiang, China.
Shan-Shan LeiDepartment of Medicine, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, 310007, China.
Zheng-Hao XuInstitute of TCM Clinical Basic Medicine, Zhejiang Chinese Medical University, Binwen Road 548, Hangzhou, 310053, China.ORCID https://orcid.org/0000-0003-0030-4701
Taizhou First People's Hospital · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis meta-analysis aims to assess the efficacy and safety of granulocyte-macrophage colony-stimulating factor (GM-CSF) antibodies on COVID-19.

methodsRelevant literatures about GM-CSF antibody treatment in COVID-19 patients were searched from the PubMed, Cochrane Library, Embase, Google scholar, and Baiduscholar databases from the COVID-19 outbreak in December 2019 until 1 January 2021. The primary outcomes included the death, intensive care unit (ICU) admission risk, ventilation requirement, and secondary infection.

resultsA total of 12 eligible literature involving 8979 COVID-19 patients were recruited, and they were divided into experimental group (

conclusionsSevere COVID-19 patients can benefit from GM-CSF antibodies.

Indexed as

AantibodyCOVID-19Granulocyte-macrophage colony-stimulating factorMeta-analysis

Identifiers

PMID34434540
PMCPMC8381424
OpenAlexW3193647203

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.