Evidence map›Paper›PMID 34435649›Full record

ArticleMolecular medicine reports2021

miR‑101a‑3p overexpression prevents acetylcholine‑CaCl

Jing Zhu, Ning Zhu, Jian Xu

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Gene Therapies in Atrial Fibrillation.Journal of cardiovascular translational research · 2025
    Review
  4. Review
  5. Article
  6. Animal and cellular models of atrial fibrillation: a review.Frontiers in cardiovascular medicine · 2025
    Review
  7. Review
  8. Research progress of non-coding RNA in atrial fibrillation.Frontiers in cardiovascular medicine · 2023
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jing ZhuDepartment of Cardiology, The First Affiliated Hospital of USTC, Hefei, Anhui 230001, P.R. China.
Ning ZhuDepartment of Respiratory Medicine, Ningbo First Hospital, Ningbo, Zhejiang 315010, P.R. China.
Jian XuDepartment of Cardiology, The First Affiliated Hospital of USTC, Hefei, Anhui 230001, P.R. China.
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF), a clinically common heart arrhythmia, can result in left ventricular hypofunction, embolism and infarction. MicroRNA (miR)‑101a‑3p is lowly expressed in atrial tissues of patients with AF, but its role in AF remains unknown. In the present study, an AF model in rats was established via intravenous injection of acetylcholine (Ach)‑CaCl

Indexed as

AcetylcholineAnimalsAtrial FibrillationCalcium ChlorideCollagenConnective Tissue Growth FactorDisease Models, AnimalDown-RegulationEnhancer of Zeste Homolog 2 ProteinFibronectinsFibrosisHeart AtriaHEK293 CellsHumansMaleMicroRNAsAcetylcholineCalcium ChlorideCCN2 protein, ratCollagenConnective Tissue Growth FactorEnhancer of Zeste Homolog 2 ProteinEZH2 protein, ratFibronectinsMicroRNAsMIRN101 microRNA, ratTgfb1 protein, ratTransforming Growth Factor beta1atrial fibrillationenhancer of zeste 2 homolog 2fibrosismicroRNA‑101a‑3prats

Identifiers

PMID34435649
PMCPMC8404104
OpenAlexW3193876420

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.