ReviewToxics2021
State of the Art on Toxicological Mechanisms of Metal and Metal Oxide Nanoparticles and Strategies to Reduce Toxicological Risks.
Review in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Copper Complexes: Emerging Micro- and Nanosystems for Dermatological Treatment.Pharmaceutics · 2026Review
- Metallic nanoparticles: from biosynthesis to biomedical applications, current scenarios and prospects.Nanoscale advances · 2026Review
- Toxicodynamics and Human Health Risks of Metal Nanoparticles: A Review of AI/ML-Based Predictive Nanotoxicology.International journal of nanomedicine · 2026Review
- Nanofertilizers in Modern Agriculture: A Technological Revolution in Plant Nutrition and Resource Efficiency.ACS omega · 2025Review
- The potential adverse human health effects of metal-containing nanoparticles: a scoping review.Journal of occupational medicine and toxicology (London, England) · 2025Review
- Biological applications of yttrium oxide nanocomposites synthesized from Aspergillus penicillioides and their potential role in environmental remediation.Scientific reports · 2025Article
- Advances in Nanomedicine: Transforming Diagnostic Imaging with Novel Contrast Agents.Current drug metabolism · 2025Review
- Metal grafted graphene-based nanomaterials towards cancer theranostic efficacy.Exploration of targeted anti-tumor therapy · 2025Review
- Nanoparticle-delivered antimicrobials for targeted suppression of bacterial wilt in peanut.Frontiers in microbiology · 2025Review
- Effect ofRSC advances · 2024Article
- Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Review
- A Systematic Genotoxicity Assessment of a Suite of Metal Oxide Nanoparticles Reveals Their DNA Damaging and Clastogenic Potential.Nanomaterials (Basel, Switzerland) · 2024Article
- Breaking the barrier: Nanoparticle-enhanced radiotherapy as the new vanguard in brain tumor treatment.Frontiers in pharmacology · 2024Review
- Inhibition ofAntibiotics (Basel, Switzerland) · 2023Article
- Nanomaterials for Skin Cancer Photoimmunotherapy.Biomedicines · 2023Review
- Role of Endoplasmic Reticulum Stress in Nano-Selenium Alleviating Prehierarchical Follicular Atresia Induced by Mercury in Laying Hens.Biological trace element research · 2022Article
- Molecular typing and prognostic model of lung adenocarcinoma based on cuprotosis-related lncRNAs.Journal of thoracic disease · 2022Article
- Crocin averts functional and structural rat hepatic disturbances induced by copper oxide nanoparticles.Toxicology research · 2022Article
- Entomopathogenic Fungi-Mediated AgNPs: Synthesis and Insecticidal Effect againstMaterials (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Metal nanoparticles have been extensively investigated for different types of pharmaceutical applications. However, their use has raised some concerns about their toxicity involving the increase of reactive oxygen species causing cellular apoptosis. Therefore, in this review we summarize the most relevant toxicity mechanisms of gold, silver, copper and copper oxide nanoparticles as well as production methods of metal nanoparticles. Parameters involved in their toxicity such as size, surface charge and concentration are also highlighted. Moreover, a critical revision of the literature about the strategies used to reduce the toxicity of this type of nanoparticles is carried out throughout the review. Additionally, surface modifications using different coating strategies, nanoparticles targeting and morphology modifications are deeply explained.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.