Evidence map›Paper›PMID 34439166›Full record

ReviewCancers2021

Atrial Fibrillation after Lung Cancer Surgery: Prediction, Prevention and Anticoagulation Management.

Gennaro Carmine Semeraro, Carlo Ambrogio Meroni, Carlo Maria Cipolla, Daniela Maria Cardinale

Abstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. Left atrial appendage occlusion in patients with cancer.Journal of thrombosis and thrombolysis · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gennaro Carmine SemeraroCardioncology Unit, European Institute of Oncology, IRCCS, 20145 Milan, MI, Italy.ORCID 0000-0003-1922-7793
Carlo Ambrogio MeroniCardiology Department, European Institute of Oncology, IRCCS, 20145 Milan, MI, Italy.
Carlo Maria CipollaCardiology Department, European Institute of Oncology, IRCCS, 20145 Milan, MI, Italy.
Daniela Maria CardinaleCardioncology Unit, European Institute of Oncology, IRCCS, 20145 Milan, MI, Italy.ORCID 0000-0002-4038-8033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is a common complication of the early postoperative period of various types of surgery, including that for lung cancer. Although induced by the homeostatic alterations related to surgery, there is evidence that it is not a mere stand-alone transitory event, but it represents a relevant complication of surgery, bearing considerable prognostic consequences. Different methods have therefore been explored to predict the occurrence of postoperative atrial fibrillation (POAF) and prevent it. In particular, the age among clinical factors, and N-terminal prohormone of brain natriuretic peptide (NT-proBNP), as a marker, have proven to be good predictors, and the use of beta-blockers or amiodarone in primary prevention seems to reduce its incidence significantly. There is growing evidence that POAF significantly increases the risk of stroke and global mortality in the long term; therefore, it should be managed in the same way as spontaneous atrial fibrillation. In this review, we will present the strongest evidence found so far and the most recent findings regarding the management of POAF, with a special focus on patients undergoing thoracic surgery for lung cancer.

Indexed as

amiodaroneanticoagulationbeta-blockerslung cancerNT-proBNPpostoperative atrial fibrillationsurgery complicationsthoracic surgery

Identifiers

PMID34439166
PMCPMC8394120

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.