Evidence map›Paper›PMID 34439776›Full record

ArticleBiomolecules2021

Sirtuin 1, Visfatin and IL-27 Serum Levels of Type 1 Diabetic Females in Relation to Cardiovascular Parameters and Autoimmune Thyroid Disease.

Magdalena Łukawska-Tatarczuk, Edward Franek, Leszek Czupryniak, Ilona Joniec-Maciejak, Agnieszka Pawlak, Ewa Wojnar, Jakub Zieliński, Dagmara Mirowska-Guzel, Beata Mrozikiewicz-Rakowska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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  5. Evaluation of Rosuvastatin Therapy onCurrent therapeutic research, clinical and experimental · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Magdalena Łukawska-TatarczukClinical Department of Internal Diseases, Endocrinology and Diabetology, Central Clinical Hospital of the Ministry of Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland.ORCID 0000-0002-0126-7669
Edward FranekClinical Department of Internal Diseases, Endocrinology and Diabetology, Central Clinical Hospital of the Ministry of Interior and Administration, Wołoska 137, 02-507 Warsaw, Poland.ORCID 0000-0002-5953-7908
Leszek CzupryniakDepartment of Diabetology and Internal Diseases, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.ORCID 0000-0003-2396-8885
Ilona Joniec-MaciejakDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CePT), Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.ORCID 0000-0002-6869-4016
Agnieszka PawlakMossakowski Medical Research Centre, Polish Academy of Sciences, Adolfa Pawińskiego 5, 02-106 Warsaw, Poland.ORCID 0000-0001-9032-9130
Ewa WojnarDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CePT), Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.ORCID 0000-0002-5511-5185
Jakub ZielińskiInterdisciplinary Centre for Mathematical and Computational Modeling, University of Warsaw, Adolfa Pawińskiego 5A, 02-106 Warsaw, Poland.
Dagmara Mirowska-GuzelDepartment of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology (CePT), Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.
Beata Mrozikiewicz-RakowskaDepartment of Diabetology and Internal Diseases, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Medical University of Warsaw · PLMinistry of Interior and Administration · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The loss of cardioprotection observed in premenopausal, diabetic women may result from the interplay between epigenetic, metabolic, and immunological factors. The aim of this study was to evaluate the concentration of sirtuin 1, visfatin, and IL-27 in relation to cardiovascular parameters and Hashimoto's disease (HD) in young, asymptomatic women with type 1 diabetes mellitus (T1DM). Thyroid ultrasound, carotid intima-media thickness (cIMT) measurement, electrocardiography, and echocardiography were performed in 50 euthyroid females with T1DM (28 with HD and 22 without concomitant diseases) and 30 controls. The concentrations of serum sirtuin 1, visfatin and IL-27 were assessed using ELISA. The T1DM and HD group had higher cIMT (

Indexed as

AdultAtherosclerosisCarotid Intima-Media ThicknessCase-Control StudiesCytokinesDiabetes Mellitus, Type 1EchocardiographyEpigenesis, GeneticFemaleGene ExpressionHashimoto DiseaseHumansInterleukinsMiddle AgedNicotinamide PhosphoribosyltransferasePremenopauseCytokinesInterleukinsMYDGF protein, humanNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanSIRT1 protein, humanSirtuin 1cardiovascular diseasefemaleIL-27sirtuin 1thyroid autoimmunitytype 1 diabetes mellitusvisfatin

Identifiers

PMID34439776
PMCPMC8391548
OpenAlexW3186019166

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.