Evidence map›Paper›PMID 34440773›Full record

ReviewCells2021

Role of High Voltage-Gated Ca

Petronel Tuluc, Tamara Theiner, Noelia Jacobo-Piqueras, Stefanie M Geisler

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Postnatal refinement of CaChannels (Austin, Tex.) · 2026
    Article
  2. Article
  3. Review
  4. Molecular medicine reports · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. MODY Only Monogenic? A Narrative Review of theInternational journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. CaAmerican journal of physiology. Endocrinology and metabolism · 2023
    Review
  13. Article
  14. Diabetes and diabesity in the view of proteomics, drug, and plant-derived remedies.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023
    Review
  15. Review
  16. Review
  17. Hyperinsulinemic Hypoglycemia Associated with a CaInternational journal of molecular sciences · 2022
    Article
  18. Frontiers in molecular neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Petronel TulucCentre for Molecular Biosciences, Department of Pharmacology and Toxicology, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.
Tamara TheinerCentre for Molecular Biosciences, Department of Pharmacology and Toxicology, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.
Noelia Jacobo-PiquerasCentre for Molecular Biosciences, Department of Pharmacology and Toxicology, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.ORCID 0000-0002-6609-2580
Stefanie M GeislerCentre for Molecular Biosciences, Department of Pharmacology and Toxicology, University of Innsbruck, Innrain 80/82, 6020 Innsbruck, Austria.ORCID 0000-0002-8898-0108
Universität Innsbruck · AT

Funding

Austrian Science Fund FWF DOC 30Austrian Science Fund FWF P 31434
6 · The paper itself

Abstract

The pancreatic islets of Langerhans secrete several hormones critical for glucose homeostasis. The β-cells, the major cellular component of the pancreatic islets, secrete insulin, the only hormone capable of lowering the plasma glucose concentration. The counter-regulatory hormone glucagon is secreted by the α-cells while δ-cells secrete somatostatin that via paracrine mechanisms regulates the α- and β-cell activity. These three peptide hormones are packed into secretory granules that are released through exocytosis following a local increase in intracellular Ca

Indexed as

Calcium SignalingIon Channel GatingAnimalsBlood GlucoseCalcium ChannelsDiabetes MellitusExocytosisHumansInsulinInsulin-Secreting CellsMembrane PotentialsSecretory PathwayBlood GlucoseCalcium ChannelsInsulinbeta celldiabetesinsulinvoltage gated calcium channel

Identifiers

PMID34440773
PMCPMC8393260
OpenAlexW3187421720

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.