Evidence map›Paper›PMID 34444675›Full record

ReviewNutrients2021

The Role of Vitamin K in Cholestatic Liver Disease.

Halima Sultana, Michio Komai, Hitoshi Shirakawa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Roles of vitamin K‑dependent protein in biomineralization (Review).International journal of molecular medicine · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Current research in food science · 2022
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Halima SultanaLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8572, Japan.
Michio KomaiLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8572, Japan.
Hitoshi ShirakawaLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, 468-1 Aramaki Aza Aoba, Aoba-ku, Sendai 980-8572, Japan.ORCID 0000-0002-4828-5274
Tohoku University · JP

Funding

Japan Society for the Promotion of Science 20H02928Japan Society for the Promotion of Science 21K14813Japan Society for the Promotion of Science The JSPS Core-to-Core Program A (Advanced Research Network) entitled "Establishment of in-ternational agricultural immunology research-core for quantum improvement in food safety"
6 · The paper itself

Abstract

Vitamin K (VK) is a ligand of the pregnane X receptor (PXR), which plays a critical role in the detoxification of xenobiotics and metabolism of bile acids. VK

Indexed as

AnimalsBile Acids and SaltsCholestasis, IntrahepaticDietary SupplementsHumansMicePregnane X ReceptorVitamin KVitamin K DeficiencyBile Acids and SaltsNR1I2 protein, humanPregnane X ReceptorVitamin Kbile acid metabolismcholestasispregnane X receptorvitamin K

Identifiers

PMID34444675
PMCPMC8400302
OpenAlexW3185957163

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.