Evidence mapPaperPMID 34444804Full record

ReviewNutrients2021

Impact of Dietary Lipids on the Reverse Cholesterol Transport: What We Learned from Animal Studies.

Bianca Papotti, Joan Carles Escolà-Gil, Josep Julve, Francesco Potì, Ilaria Zanotti

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Bianca PapottiDipartimento di Scienze degli Alimenti e del Farmaco, Università di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0003-3916-7003
Joan Carles Escolà-GilInstitut de Recerca de l'Hospital de la Santa Creu i Sant Pau & Institut d'Investigació Biomèdica (IIB) Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0001-9021-2485
Josep JulveInstitut de Recerca de l'Hospital de la Santa Creu i Sant Pau & Institut d'Investigació Biomèdica (IIB) Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0002-6531-2246
Francesco PotìUnità di Neuroscienze, Dipartimento di Medicina e Chirurgia, Università di Parma, Via Volturno 39/F, 43125 Parma, Italy.ORCID 0000-0002-1708-0719
Ilaria ZanottiDipartimento di Scienze degli Alimenti e del Farmaco, Università di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.ORCID 0000-0003-2701-6021
University of Parma · ITHospital de Sant Pau · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reverse cholesterol transport (RCT) is a physiological mechanism protecting cells from an excessive accumulation of cholesterol. When this process begins in vascular macrophages, it acquires antiatherogenic properties, as has been widely demonstrated in animal models. Dietary lipids, despite representing a fundamental source of energy and exerting multiple biological functions, may induce detrimental effects on cardiovascular health. In the present review we summarize the current knowledge on the mechanisms of action of the most relevant classes of dietary lipids, such as fatty acids, sterols and liposoluble vitamins, with effects on different steps of RCT. We also provide a critical analysis of data obtained from experimental models which can serve as a valuable tool to clarify the effects of dietary lipids on cardiovascular disease.

Indexed as

Biological TransportCholesterolDietary FatsAnimalsCardiovascular DiseasesCholesterol, HDLFatty AcidsHumansMacrophagesModels, AnimalRodentiaCholesterolCholesterol, HDLDietary FatsFatty Acidsfatty acidsHDLreverse cholesterol transportrodentssterols

Identifiers

PMID34444804
PMCPMC8401548
OpenAlexW3191214115

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.