Evidence map›Paper›PMID 34445769›Full record

ReviewInternational journal of molecular sciences2021

Analysis of the Potential Genetic Links between Psoriasis and Cardiovascular Risk Factors.

Dorota Purzycka-Bohdan, Anna Kisielnicka, Michał Bohdan, Aneta Szczerkowska-Dobosz, Marta Sobalska-Kwapis, Bogusław Nedoszytko, Roman J Nowicki

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. New Insights into Psoriasis.International journal of molecular sciences · 2022
    Article
  10. Review
  11. Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dorota Purzycka-BohdanDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-6089-8030
Anna KisielnickaDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Michał BohdanFirst Department of Cardiology, Medical University of Gdansk, 80-211 Gdansk, Poland.ORCID 0000-0002-3496-2238
Aneta Szczerkowska-DoboszDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Marta Sobalska-KwapisBiobank Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 90-231 Lodz, Poland.
Bogusław NedoszytkoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0002-6286-0693
Roman J NowickiDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.ORCID 0000-0003-4768-1387

Funding

the Polish Ministry of Science and Higher Education 02-0066/07/253
6 · The paper itself

Abstract

Cardiovascular risk factors are one of the most common comorbidities in psoriasis. A higher prevalence of hypertension, insulin resistance and type 2 diabetes, dyslipidemia, obesity, metabolic syndrome, depression, as well as cardiovascular disease was confirmed in psoriatic patients in comparison to the general population. Data suggest that psoriasis and systemic inflammatory disorders may originate from the pleiotropic interactions with many genetic pathways. In this review, the authors present the current state of knowledge on the potential genetic links between psoriasis and cardiovascular risk factors. The understanding of the processes linking psoriasis with cardiovascular risk factors can lead to improvement of psoriasis management in the future.

Indexed as

AnimalsCardiovascular DiseasesGenetic Predisposition to DiseaseHeart Disease Risk FactorsHumansPsoriasisRisk Factorscardiovascular riskcomorbiditiesgenetic backgroundpsoriasis

Identifiers

PMID34445769
PMCPMC8396451

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.