Evidence map›Paper›PMID 34448631›Full record

ArticleEuropean journal of mass spectrometry (Chichester, England)2021

Identification of newly formed toxic chemicals in E-cigarette aerosols with Orbitrap mass spectrometry and implications on E-cigarette control.

Beizhan Yan, Dimitri Zagorevski, Vesna Ilievski, Norman J Kleiman, Diane B Re, Ana Navas-Acien, Markus Hilpert

Open access · greenAbstract read
In one paragraph

Article in European journal of mass spectrometry (Chichester, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Beizhan Yan57699Lamont-Doherty Earth Observatory of Columbia University, USA.ORCID https://orcid.org/0000-0002-1321-779X
Dimitri ZagorevskiCenter for Biotechnology and Interdisciplinary Studies, 8024Rensselaer Polytechnic Institute, USA.
Vesna IlievskiDepartment of Environmental Health Sciences, 33638Mailman School of Public Health, Columbia University, USA.
Norman J KleimanDepartment of Environmental Health Sciences, 33638Mailman School of Public Health, Columbia University, USA.ORCID https://orcid.org/0000-0002-4725-998X
Diane B ReDepartment of Environmental Health Sciences, 33638Mailman School of Public Health, Columbia University, USA.
Ana Navas-AcienDepartment of Environmental Health Sciences, 33638Mailman School of Public Health, Columbia University, USA.
Markus HilpertDepartment of Environmental Health Sciences, 33638Mailman School of Public Health, Columbia University, USA.
Columbia University · USLamont-Doherty Earth Observatory · USRensselaer Polytechnic Institute · US

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Diane Berengere Re · 1998 to 2026
$44.7M
The Exposure to Metals from E-Cigarettes (EMIT) StudyR01ES030025 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI RULE, ANA MARIA · 2018 to 2020
$1.5M
Tracking Metals From E-cigarettes: From The Coil Into Lung TissueR21ES029777 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HILPERT, MARKUS, KLEIMAN, NORMAN J · 2018 to 2019
$438k
Acquisition of a Sensitive QTrap LC/MS/MS System for Biomarker AnalysesS10OD020058 · OD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YAN, BEIZHAN · 2016 to 2016
$413k
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES030025NIEHS NIH HHS R21 ES029777NIH HHS S10 OD020058
6 · The paper itself

Abstract

The increasing use of electronic nicotine delivery systems (ENDS) is of concern due to multiple emerging adverse health effects. Most analyses of the harmful chemicals of ENDS have targeted metals or carbonyls generated by thermal decomposition of carrier liquids such as propylene glycol. However, new complex compounds not routinely identified and with unknown health consequences could be formed. ENDS aerosol samples were collected by the direct aerosol droplet deposition method. Untargeted analysis was performed using Orbitrap mass spectrometry with high mass accuracy. We identified more than 30 "features" in the aerosol characterized by pairs of the mass-to-charge ratio "

Indexed as

Electronic Nicotine Delivery SystemsVapingAdolescentAerosolsChildFemaleHumansMass SpectrometryNicotinePregnancyAerosolsNicotineaerosoldevelopmental toxicityE-cigarette controltoxicityUntargeted analysisvaping

Identifiers

PMID34448631
PMCPMC9035225
OpenAlexW3195182946

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.