Evidence map›Paper›PMID 34452347›Full record

ArticleViruses2021

Pathology and Pathogenesis of Eurasian Blackbirds (

Giuseppe Giglia, Gianfilippo Agliani, Bas B Oude Munnink, Reina S Sikkema, Maria Teresa Mandara, Elvio Lepri, Marja Kik, Jooske Ijzer, Jolianne M Rijks, Christine Fast and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 39 citations in OpenAlex.

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  16. Usutu virus avian and human infection after more than 25 years of circulation.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Giuseppe GigliaDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.ORCID 0000-0002-3544-8812
Gianfilippo AglianiDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Bas B Oude MunninkDepartment of Viroscience, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.
Reina S SikkemaDepartment of Viroscience, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0001-7331-6274
Maria Teresa MandaraDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.
Elvio LepriDepartment of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy.ORCID 0000-0001-8478-8154
Marja KikDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Jooske IjzerDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Jolianne M RijksDutch Wildlife Health Centre, Utrecht University, 3584 CL Utrecht, The Netherlands.
Christine FastInstitute of Novel and Emerging Infectious Disease, Friedrich-Loeffler Institut, D-17493 Isle of Riems, Germany.ORCID 0000-0002-7341-7873
Marion P G KoopmansDepartment of Viroscience, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0002-5204-2312
Monique H VerheijeDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.ORCID 0000-0003-1274-2987
Andrea GröneDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Chantal B E M ReuskenDepartment of Viroscience, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.
Judith M A van den BrandDivision of Pathology, Department of Biomedical Health Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.ORCID 0000-0001-8420-5406
Utrecht University · NLUniversity of Perugia · ITFriedrich-Loeffler-Institut · DENational Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Usutu virus (USUV) is a mosquito-borne zoonotic flavivirus. Despite its continuous circulation in Europe, knowledge on the pathology, cellular and tissue tropism and pathogenetic potential of different circulating viral lineages is still fragmentary. Here, macroscopic and microscopic evaluations are performed in association with the study of cell and tissue tropism and comparison of lesion severity of two circulating virus lineages (Europe 3; Africa 3) in 160 Eurasian blackbirds (Turdus merula) in the Netherlands. Results confirm hepatosplenomegaly, coagulative necrosis and lymphoplasmacytic inflammation as major patterns of lesions and, for the first time, vasculitis as a novel virus-associated lesion. A USUV and

Indexed as

AnimalsBird DiseasesFlavivirusFlavivirus InfectionsNetherlandsPasseriformesPhagocytesVirulenceavian malariaEurasian blackbirdsimmunohistochemistrypathologyplasmodiumtissue tropismUsutu virus

Identifiers

PMID34452347
PMCPMC8402641
OpenAlexW3187072101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.