Evidence map›Paper›PMID 34458276›Full record

ReviewFrontiers in cell and developmental biology2021

The Multifaceted Roles of Proline in Cell Behavior.

Eduardo J Patriarca, Federica Cermola, Cristina D'Aniello, Annalisa Fico, Ombretta Guardiola, Dario De Cesare, Gabriella Minchiotti

Abstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
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  7. A mechanistic study on the enhanced antihypertensive effects of aFrontiers in cell and developmental biology · 2026
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eduardo J PatriarcaStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Federica CermolaStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Cristina D'AnielloStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Annalisa FicoStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Ombretta GuardiolaStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Dario De CesareStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.
Gabriella MinchiottiStem Cell Fate Laboratory, Institute of Genetics and Biophysics "A. Buzzati Traverso", Consiglio Nazionale delle Ricerche, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is:

Indexed as

antistress activitycell plasticityenergy sourceextracellular proteinsmetabolismneural toxicityproline metabolismsignaling modulators

Identifiers

PMID34458276
PMCPMC8397452

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.