Evidence map›Paper›PMID 34458333›Full record

ArticleFrontiers in cardiovascular medicine2021

Diabetes Promotes Retinal Vascular Endothelial Cell Injury by Inducing CCN1 Expression.

Haicheng Li, Ting Li, Heting Wang, Xuemin He, Ying Li, Siying Wen, Rongdong Peng, Yuanpeng Nie, Yan Lu, He Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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  12. CCN proteins: opportunities for clinical studies-a personal perspective.Journal of cell communication and signaling · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Haicheng LiDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Ting LiDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Heting WangDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Xuemin HeDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Ying LiCancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Siying WenDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Rongdong PengDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yuanpeng NieDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yan LuDepartment of Clinical Immunology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
He YangCancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Yinong YeFoshan Fourth People's Hospital, Foshan, China.
Guojun ShiDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yanming ChenDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Third Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CNNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CCN1diabetic retinopathyNOX4 NADPH oxidaseoxidative stresstight junction

Identifiers

PMID34458333
PMCPMC8385274
OpenAlexW3194636861

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.