Evidence map›Paper›PMID 34460310›Full record

ArticleJournal of bacteriology2021

Spontaneous Mutants of Streptococcus sanguinis with Defects in the Glucose-Phosphotransferase System Show Enhanced Post-Exponential-Phase Fitness.

Lin Zeng, Alejandro R Walker, Kyulim Lee, Zachary A Taylor, Robert A Burne

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Systematic analysis of the glucose-PTS inApplied and environmental microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lin ZengDepartment of Oral Biology, University of Floridagrid.15276.37 College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-9269-2707
Alejandro R WalkerDepartment of Oral Biology, University of Floridagrid.15276.37 College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-5839-6584
Kyulim LeeDepartment of Oral Biology, University of Floridagrid.15276.37 College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-4119-3086
Zachary A TaylorDepartment of Oral Biology, University of Floridagrid.15276.37 College of Dentistry, Gainesville, Florida, USA.
Robert A BurneDepartment of Oral Biology, University of Floridagrid.15276.37 College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0002-4234-0316
University of Florida · US

Funding

GENE REGULATION AND PHYSIOLOGY OF STREPTOCOCCUS MUTANSR01DE012236 · NIDCR · UNIVERSITY OF ROCHESTER · PI Lin Zeng · 1997 to 2026
$8.5M
NIDCR NIH HHS DE12236NIDCR NIH HHS R01 DE012236
6 · The paper itself

Abstract

Genetic truncations in a gene encoding a putative glucose-phosphotransferase system (PTS) protein (

Indexed as

Bacterial ProteinsDNA, BacterialGene DeletionGene Expression Regulation, BacterialGlucoseHydrogen PeroxideLactic AcidPhosphotransferasesPyruvic AcidStreptococcus sanguisBacterial ProteinsDNA, BacterialGlucoseHydrogen PeroxideLactic AcidPhosphotransferasesPyruvic Acidbacterial persistencecarbohydrate metabolismglucose-PTSpyruvate metabolismsingle-nucleotide polymorphismStreptococcus sanguinis

Identifiers

PMID34460310
PMCPMC8544416
OpenAlexW3198910214

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.