Evidence map›Paper›PMID 34476519›Full record

ArticleAnalytical and bioanalytical chemistry2021

Investigation of stationary phases performance for eicosanoids profiling in RP-HPLC.

Kodjo Nouwade, Sana Tfaili, Pierre Chaminade

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kodjo NouwadeUniversité Paris-Saclay, Lipides : systèmes analytiques et biologiques, 92296, Châtenay-Malabry, France.
Sana TfailiUniversité Paris-Saclay, Lipides : systèmes analytiques et biologiques, 92296, Châtenay-Malabry, France. sana.tfaili@universite-paris-saclay.fr.ORCID http://orcid.org/0000-0002-6256-6777
Pierre ChaminadeUniversité Paris-Saclay, Lipides : systèmes analytiques et biologiques, 92296, Châtenay-Malabry, France.
Université Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eicosanoids - oxidative derivatives from arachidonic acid - represent biologically active lipid mediators in inflammatory processes. Different analytical methods treat eicosanoid analysis. Among which, reverse phase liquid chromatography figures as the appropriate method for eicosanoid profiling. RP-HPLC for eicosanoid analysis is often conducted on C18 columns. Some studies focused on profiling one family of eicosanoids; others considered all eicosanoid families. In both cases, co-elution remained a major issue and detection in mass spectrometry partially resolves this problem. In fact, the mass transitions used to monitor eicosanoid species are not specific enough and many isobars can be listed. For this, optimizing the RP-HPLC separation remains important. Based on the parameter F

Indexed as

AlgorithmsChromatography, High Pressure LiquidChromatography, Reverse-PhaseEicosanoidsHydrophobic and Hydrophilic InteractionsPorositySilicon DioxideEicosanoidsSilicon DioxideAccucore C30EicosanoidsHydrophobic-subtraction modelPeak capacity per minuteSelectivityTime needed

Identifiers

PMID34476519
OpenAlexW3198361120

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.