Evidence map›Paper›PMID 34481746›Full record

ArticleObesity research & clinical practice

Use of continuous glucose monitoring in obesity research: A scoping review.

Elizabeth Hegedus, Sarah-Jeanne Salvy, Choo Phei Wee, Monica Naguib, Jennifer K Raymond, D Steven Fox, Alaina P Vidmar

Abstract readScoping Review
In one paragraph

Article in Obesity research & clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  17. Continuous Glucose Monitoring in Children and Adolescents with Congenital Adrenal HyperplasiaJournal of clinical research in pediatric endocrinology · 2023
    Observational
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elizabeth HegedusChildren's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, Los Angeles, CA, United States.
Sarah-Jeanne SalvyCancer Research Center on Health Equity, Cedars-Sinai Medical Center, West Hollywood, CA, United States.
Choo Phei WeeSouthern California Clinical and Translational Science Institute, Department of Preventive Medicine, Keck School of Medicine, Los Angeles, CA, United States.
Monica NaguibChildren's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, Los Angeles, CA, United States.
Jennifer K RaymondChildren's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, Los Angeles, CA, United States.
D Steven FoxDepartment of Pharmaceutical and Health Economics, School of Pharmacy of the University of Southern California, Los Angeles, CA, United States.
Alaina P VidmarChildren's Hospital Los Angeles and Keck School of Medicine of USC, Center for Endocrinology, Diabetes and Metabolism, Los Angeles, CA, United States. Electronic address: avidmar@chla.usc.edu.

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Project 2: Leveraging Ongoing Home Visitation Programs to Address Obesity Disparities among Underserved, Low-Income Mothers and ChildrenU54MD000502 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SALVY, SARAH-JEANNE · 2017 to 2022
$11.8M
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and ModeratorsR01CA258222 · NCI · CEDARS-SINAI MEDICAL CENTER · PI FIGUEIREDO, JANE C., PETERSON, COURTNEY MARIE · 2021 to 2025
$4.1M
In-home obesity prevention to reach low-income infants through maternal and social transmissionR01HD092483 · NICHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DE LA HAYE, KAYLA, SALVY, SARAH-JEANNE · 2017 to 2021
$2.7M
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCI NIH HHS R01 CA258222NICHD NIH HHS R01 HD092483NIMHD NIH HHS U54 MD000502
6 · The paper itself

Abstract

backgroundThis scoping review provides a timely synthesis of the use of continuous glucose monitoring in obesity research with considerations to adherence to continuous glucose monitor devices and metrics most frequently reported.

methodsThis scoping review was conducted adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. Eligible studies (n = 31) evaluated continuous glucose monitor use in research on participants, of all ages, with overweight or obesity.

resultsReviewed studies varied in duration from one to 84 days (mean: 8.74 d, SD 15.2, range 1-84 d) with 889 participants total (range: 11-118 participants). Across all studies, the mean percent continuous glucose monitor wear time (actual/intended wear time in days) was 92% (numerator - mean: 266.1 d, SD: 452, range: 9-1596 d/denominator - mean: 271.6 d, SD: 451.5, range: 9-1596 d). Continuous glucose monitoring was utilized to provide biofeedback (n = 2, 6%), monitor dietary adherence (n = 2, 6%), and assess glycemic variability (n = 29, 93%). The most common variability metrics reported were standard deviation (n = 19, 62%), area under the curve (n = 12, 39%), and glycemic range (n = 12, 39%).

conclusionsAvailable evidence suggests that continuous glucose monitoring is a well-tolerated and versatile tool for obesity research in pediatric and adult patients. Future investigation is needed to substantiate the feasibility and utility of continuous glucose monitors in obesity research and maximize comparability across studies.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringChildHumansObesityBlood GlucoseAdherenceContinuous glucose monitorObesityOverweight

Identifiers

PMID34481746
PMCPMC8502209

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.