Evidence map›Paper›PMID 34483852›Full record

ReviewFrontiers in systems neuroscience2021

Infant Attachment and Social Modification of Stress Neurobiology.

Katherine Packard, Maya Opendak, Caroline Davis Soper, Haniyyah Sardar, Regina M Sullivan

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Katherine PackardEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.
Maya OpendakEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.
Caroline Davis SoperChild Study Center, Child & Adolescent Psychiatry, New York University Langone Medical Center, New York University School of Medicine, New York, NY, United States.
Haniyyah SardarEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.
Regina M SullivanEmotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.

Funding

Maternal Influence Over Prefrontal Cortex and Transition to Independence - Revision - 2R37HD083217 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SULLIVAN, REGINA MARIE · 2015 to 2024
$4.7M
Neurobiology of Social Behavior: Circuit Analysis in Early LifeR00MH124434 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI OPENDAK, MAYA · 2022 to 2024
$961k
Neurobiology of Social Behavior: Circuit Analysis in Early LifeK99MH124434 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OPENDAK, MAYA · 2020 to 2021
$209k
NICHD NIH HHS R37 HD083217NIMH NIH HHS K99 MH124434NIMH NIH HHS R00 MH124434
6 · The paper itself

Abstract

Decades of research have informed our understanding of how stress impacts the brain to perturb behavior. However, stress during development has received specific attention as this occurs during a sensitive period for scaffolding lifelong socio-emotional behavior. In this review, we focus the developmental neurobiology of stress-related pathology during infancy and focus on one of the many important variables that can switch outcomes from adaptive to maladaptive outcome: caregiver presence during infants' exposure to chronic stress. While this review relies heavily on rodent neuroscience research, we frequently connect this work with the human behavioral and brain literature to facilitate translation. Bowlby's Attachment Theory is used as a guiding framework in order to understand how early care quality impacts caregiver regulation of the infant to produce lasting outcomes on mental health.

Indexed as

amygdalaattachmentcorticosteroneinfantsocial

Identifiers

PMID34483852
PMCPMC8415781

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.