Evidence map›Paper›PMID 34483880›Full record

ArticleFrontiers in aging neuroscience2021

Prostaglandin E

Amanda C Rosehart, Thomas A Longden, Nick Weir, Jackson T Fontaine, Anne Joutel, Fabrice Dabertrand

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Cerebral capillary computation.American journal of physiology. Cell physiology · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. PIPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Electrocalcium coupling in brain capillaries: Rapidly traveling electrical signals ignite local calcium signals.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Vascular Function and Ion Channels in Alzheimer's Disease.Microcirculation (New York, N.Y. : 1994) · 2024
    Review
  16. Electro-metabolic signaling.The Journal of general physiology · 2024
    Article
  17. Cracking the Endothelial Calcium (CaInternational journal of molecular sciences · 2023
    Review
  18. Review
  19. Neurophotonics · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Amanda C RosehartDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Thomas A LongdenDepartment of Physiology, School of Medicine, University of Maryland, Baltimore, Baltimore, MD, United States.
Nick WeirDepartment of Physiology, School of Medicine, University of Maryland, Baltimore, Baltimore, MD, United States.
Jackson T FontaineDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Anne JoutelINSERM, UMR 1266, GHU Paris Psychiatrie et Neurosciences, Institute of Psychiatry and Neuroscience of Paris, University of Paris, Paris, France.
Fabrice DabertrandDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
University of Colorado Anschutz Medical Campus · USUniversity of Maryland, Baltimore · USUniversity of Vermont · US

Funding

Capillary control of cerebral blood flow, and its disruption in small vessel diseaseR01HL136636 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Fabrice Dabertrand · 2017 to 2026
$3.8M
Pericytes as metabolic sentinels in the control of brain blood flow in health and Alzheimer's diseaseR01AG066645 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Thomas A Longden · 2020 to 2026
$2.5M
NHLBI NIH HHS R01 HL136636NIA NIH HHS R01 AG066645
6 · The paper itself

Abstract

Prostaglandin E

Indexed as

CADASILcerebral small vessel diseasesepidermal growth factor receptorfunctional hyperemiamicrocirculationneurovascular couplingpotassium channelprostaglandin E2

Identifiers

PMID34483880
PMCPMC8414797
OpenAlexW3197639791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.