ArticleJournal of animal science2021
Inulin and isomalto-oligosaccharide alleviate constipation and improve reproductive performance by modulating motility-related hormones, short-chain fatty acids, and feces microflora in pregnant sows.
Article in Journal of animal science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 21 citations in OpenAlex.
- Dietary fiber sources affect reproductive and lactation outcomes and colostrum protein concentration in sows.Tropical animal health and production · 2026Article
- The Effects of Vitamin DAnimals : an open access journal from MDPI · 2026Article
- Maternal and infant gut microbiome.iMeta · 2026Review
- Gestational constipation and the gut microbiota: mechanisms, interventions, and implications for maternal and offspring health.Frontiers in nutrition · 2026Review
- Effect of supplementation with different dietary energy sources on semen quality in a cold-stressed boar model.Animal biotechnology · 2025Article
- Effect of Dietary Neutral Detergent Fiber Intake on Improving Fecal Consistency in Gestating Gilts.Animals : an open access journal from MDPI · 2025Article
- Dietary inulin supplementation in early gestation regulates uterine fluid exosomes and angiogenesis to improve embryo implantation in sows.Journal of animal science and biotechnology · 2025Article
- Dietary fibre supplementation in late gestation modulates gut microbiota and improves reproductive performance and colostrum quality in sows.Frontiers in microbiology · 2025Article
- Laxative effect of Zengye granule by modulating the SCF/c-Kit pathway and gut microbiota in constipated mice.Frontiers in veterinary science · 2025Article
- Maternal supplementation with konjac glucomannan and κ-carrageenan promotes sow performance and benefits the gut barrier in offspring.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Effect of Dietary Sugarcane Bagasse on Reproductive Performance, Constipation, and Gut Microbiota of Gestational Sows.Animals : an open access journal from MDPI · 2024Article
- Maternal or post-weaning dietary fructo-oligosaccharide supplementation reduces stillbirth rate of sows and diarrhea of weaned piglets.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- The effect ofFrontiers in veterinary science · 2024Article
- Probiotics alleviate constipation and inflammation in late gestating and lactating sows.NPJ biofilms and microbiomes · 2023Article
- Longitudinal Investigation of Enteric Virome Signatures from Parental-Generation to Offspring Pigs.Microbiology spectrum · 2023Article
- Research progress on anti-stress nutrition strategies in swine.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Review
- Article
- Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis.Molecular medicine reports · 2022Article
- The Improvement of Semen Quality by Dietary Fiber Intake Is Positively Related With Gut Microbiota and SCFA in a Boar Model.Frontiers in microbiology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Constipation in gestating and lactating sows is common and the inclusion of dietary fiber may help to alleviate this problem. We investigated the effects of inulin (INU) and isomalto-oligosaccharide (IMO), two sources of soluble dietary fiber, on gastrointestinal motility-related hormones, short-chain fatty acids (SCFA), fecal microflora, and reproductive performance in pregnant sows. On day 64 of gestation, 30 sows were randomly divided into three groups and fed as follows: a basal diet, a basal diet with 0.5% INU, and a basal diet with 0.5% IMO. We found that INU and IMO significantly modulated the levels of gastrointestinal motility-related hormones, as evidenced by an increase in substance P (P < 0.05), and a decrease in the vasoactive intestinal peptide concentrations (P < 0.05), indicating the capacity of INU and IMO to alleviate constipation. Furthermore, IMO enhanced the concentrations of acetic, propionic, isobutyric, butyric, isovaleric, and valeric acids in the feces (P < 0.05). High-throughput sequencing showed that IMO and INU increased the fecal microflora α- and β-diversity (P < 0.05). Methanobrevibacter was more abundant (P < 0.05), whereas the richness of Turicibacter was lower in the INU and IMO groups than in the control group (P < 0.05). In addition, IMO significantly increased litter size (P < 0.05). Overall, our findings indicate that INU and IMO can relieve constipation, optimize intestinal flora, and promote reproductive performance in pregnant sows.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.