ReviewThe journal of allergy and clinical immunology. In practice2021
Nonrespiratory Comorbidities in Asthma.
Review in The journal of allergy and clinical immunology. In practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Aspirin Dosing for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Chronic Obstructive Pulmonary Disease and Asthma: Insights From ADAPTABLE.Journal of the American Heart Association · 2025Trial
- Untargeted metabolomic profiling of childhood asthma: An exploratory analysis of anthropogenic chemicals and the serum metabolome.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Pulmonary microbiota-associated formononetin modulates microglial activation in asthma-related anxiety.Journal of neuroinflammation · 2026Article
- The impact of denosumab and calcitriol on asthma risk and lung function: a drug target mendelian randomization study.European journal of clinical pharmacology · 2026Article
- Assessing the comorbidity between asthma and depression through polygenic risk scoring and time-to-event models.BMC medicine · 2026Article
- Ambulatory blood pressure profiles of children with asthma compared to healthy controls.Pediatric nephrology (Berlin, Germany) · 2025Article
- Connections and Unmet Needs: Severe Asthma Biologics and Osteoporosis.Biomedicines · 2025Review
- Prevalence of Obesity and Its Associated Comorbidities in Adults with Asthma: A Single-Center Study in Saudi Arabia.Medicina (Kaunas, Lithuania) · 2024Article
- Distinct enterotypes and dysbiosis: unraveling gut microbiota in pulmonary and critical care medicine inpatients.Respiratory research · 2024Article
- Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999-2018.BMC public health · 2024Article
- Moderate-High Blood Eosinophilia Is Associated with Increased Hospitalization and Other Asthma Comorbidities.Biomolecules · 2024Review
- Thyroid Diseases in a Cohort of Finnish Patients with Hidradenitis Suppurativa.Skin appendage disorders · 2023Article
- Pediatric and adult asthma clinical phenotypes: a real world, big data study based on acute exacerbations.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Hidden Comorbidities in Asthma: A Perspective for a Personalized Approach.Journal of clinical medicine · 2023Review
- Allergic rhinitis and other comorbidities associated with asthma control in Thailand.Frontiers in medicine · 2023Article
- Asthma in pregnancy.Allergy and asthma proceedings · 2023Review
- The associations between asthma and common comorbidities: a comprehensive Mendelian randomization study.Frontiers in medicine · 2023Article
- Application of Precision-Cut Lung Slices as an In Vitro Model for Research of Inflammatory Respiratory Diseases.Bioengineering (Basel, Switzerland) · 2022Review
- Increased Risk of Hypothyroidism in People with Asthma: Evidence from a Real-World Population-Based Study.Journal of clinical medicine · 2022Article
- [Consensus document for Severe Asthma. 2025 Update].Open respiratory archivesArticle
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
Asthma is a chronic heterogeneous airway disease. Common comorbid conditions are often disproportionately present in severe asthma. Optimal care of patients with asthma requires the recognition and treatment of these comorbid conditions. This review outlines the pathophysiological mechanisms between nonrespiratory comorbid conditions and asthma and their effect on asthma outcomes. They include: type 2 diabetes mellitus, hypertension, atherosclerotic cardiovascular disease, adrenal and thyroid gland diseases, pregnancy, osteoporosis, adverse effects from medications, and mental health disorders. Studies indicate how poor glycemic control of type 2 diabetes mellitus is associated with not only greater health care utilization but poorer asthma outcomes. Also, a large health care claims database indicates that a substantial proportion of pregnant women have uncontrolled asthma and are prescribed suboptimal controller therapy. Additional data about these nonrespiratory comorbidities and medications known to benefit both nonrespiratory comorbidities and asthma are necessary.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.