Evidence map›Paper›PMID 34495401›Full record

SynthesisClinical oral investigations2021

Prevalence of red and orange microbial complexes in endodontic-periodontal lesions: a systematic review and meta-analysis.

Diego José Gambin, Filipe Colombo Vitali, João Paulo De Carli, Ricardo Ruiz Mazzon, Brenda P F A Gomes, Thais Mageste Duque, Micheline Sandini Trentin

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
  5. The dual roles ofFrontiers in oncology · 2026
    Review
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  7. Review
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  11. Review
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  14. Frontiers in microbiology · 2022
    Article
  15. The oral microbiome in young women at different stages of periodontitis:Frontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diego José GambinPost-Graduate Program in Dentistry, Faculty of Dentistry, University of Passo Fundo, Av. Brasil Leste, São José, Passo Fundo, RS, 28599052-900, Brazil.
Filipe Colombo VitaliDepartment of Dentistry, Post-Graduate Program in Dentistry, Federal University of Santa Catarina (UFSC), Av. Delfino Conti, s/n-Trindade, Florianópolis, SC, 88040-900, Brazil.
João Paulo De CarliDepartment of Oral Medicine and Prosthodontics, University of Passo Fundo, Av. Brasil Leste, São José, Passo Fundo, RS, 28599052-900, Brazil.
Ricardo Ruiz MazzonDepartment of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina (UFSC), Av. Delfino Conti, s/n-Trindade, Florianópolis, SC, 88040-900, Brazil.
Brenda P F A GomesDepartment of Restorative Dentistry, Division of Endodontics, Piracicaba Dental School, State University of Campinas-UNICAMP, Av. LimeiraPiracicaba, AreiãoSP, 90113414-903, Brazil.
Thais Mageste DuqueDepartment of Dentistry, Federal University of Santa Catarina (UFSC), Av. Delfino Conti, s/n-Trindade, Florianópolis, SC, 88040-900, Brazil. thaismageste@yahoo.com.br.ORCID http://orcid.org/0000-0003-2265-8690
Micheline Sandini TrentinDepartment of Periodontics, Faculty of Dentistry, University of Passo Fundo, Av. Brasil Leste, São José, Passo Fundo, RS, 28599052-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis systematic review assesses the prevalence of microbial complexes in endodontic-periodontal lesion. MATERIALS AND

methodsNine databases were searched through August 2020. Experts were consulted to indicate additional studies. Studies were blindly selected by two reviewers based on pre-defined eligibility criteria. Studies that evaluated the prevalence of microbial orange and red complexes among patients with endodontic-periodontal lesion were considered eligible. Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data.

resultsFrom 572 articles found on all databases, 11 clinical studies were finally included. The following microorganisms were investigated: P. gingivalis, T. forsythia, T. denticola, F. nucleatum, F. periodonticum, P. micra, P. intermedia, P. nigrescens, S. constellatus, C. gracilis, C. rectus, C. showae and E. nodatum. Considering the orange complex, P. micra, E. nodatum and S. constellatus were prevalent in both root canal and periodontal pockets. P. gingivalis and T. forsythia belonging to the red complex were prevalent only in periodontal pockets. The red complex microorganisms were not found very frequently in root canal.

conclusionsThere is a similarity between the microbiome of root canal and periodontal pockets, with prevalence of the three microorganisms of the orange complex. Two microorganisms from the red complex were prevalent only in periodontal pockets. CLINICAL RELEVANCE: The prevalence of specific microorganisms in endodontic-periodontal lesion is important to understand the microbiological profile of the patients involved and to correlate it with possible clinical and repair conditions of this pathology.

Indexed as

Citrus sinensisMicrobiotaHumansPeriodontal PocketPorphyromonas gingivalisPrevalenceRoot Canal TherapyEndodonticsMeta-analysisPeriodontal diseasesPeriodonticsSystematic review

Identifiers

PMID34495401

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.