Evidence map›Paper›PMID 34495684›Full record

ArticleMolecular biology of the cell2021

Evidence for a nuclear role for

Katherine A Sharp, Mark J Khoury, Frederick Wirtz-Peitz, David Bilder

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katherine A SharpDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley CA 94720.ORCID 0000-0002-7574-7331
Mark J KhouryDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley CA 94720.ORCID 0000-0002-7211-0247
Frederick Wirtz-PeitzDepartment of Genetics, Harvard Medical School, Boston, MA 02115.
David BilderDepartment of Molecular and Cell Biology, University of California-Berkeley, Berkeley CA 94720.ORCID 0000-0002-1842-4966
University of California, Berkeley · USHarvard University · US

Funding

Polarity, growth, and morphogenesis of epitheliaR35GM130388 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI David Bilder · 2019 to 2026
$6.5M
Mechanisms of Drosophila Tumor SuppressionR01GM090150 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID · 2010 to 2018
$2.0M
Phinney - Orbitrap Fusion ETDS10OD021801 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PHINNEY, BRETT S · 2016 to 2016
$600k
NIGMS NIH HHS R01 GM090150NIGMS NIH HHS R35 GM130388NIH HHS S10 OD021801
6 · The paper itself

Abstract

Scribble (Scrib), Discs-large (Dlg), and Lethal giant larvae (Lgl) are basolateral regulators of epithelial polarity and tumor suppressors whose molecular mechanisms of action remain unclear. We used proximity biotinylation to identify proteins localized near Dlg in the

Indexed as

AnimalsCell PolarityCytoskeletal ProteinsDrosophila melanogasterDrosophila ProteinsEpithelial CellsEpitheliumImaginal DiscsMembrane ProteinsMi-2 Nucleosome Remodeling and Deacetylase ComplexNuclear ProteinsProtein Kinase CTranscription FactorsTumor Suppressor ProteinsCytoskeletal Proteinsdlg1 protein, DrosophilaDrosophila Proteinsl(2)gl protein, DrosophilaMembrane ProteinsMi-2 Nucleosome Remodeling and Deacetylase ComplexNuclear ProteinsProtein Kinase CScrib protein, DrosophilaTranscription FactorsTumor Suppressor Proteins

Identifiers

PMID34495684
PMCPMC8693970
OpenAlexW3196522150

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.